Molecular Target Synopsis
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ZNF347 (Q96SE7) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 09/07/2019)
Structural Druggability Help: Help

Chain-based assessment (last updated 09/07/2019)


Chains assessed16
Chains with at least one site assessed as druggable using the strict criteria0
Chains with at least one site assessed as druggable using the relaxed criteria0


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
2EN4_A Zinc finger protein 347 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.31 53.8 16.6 No No
2 empty 2.51 52.9 19.8 No No
3 empty 2.47 51 9.2 No No
4 empty 2.67 55.9 9 No No
5 empty 2.14 54.1 11.7 No No
6 empty 2.58 59.6 6.2 No No
7 empty 1.49 56 6 No No
8 empty 3 48.9 6.3 No No
2YTI_A Zinc finger protein 347 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.32 50.1 19.6 No No
2 empty 2.1 49.6 10.8 No No
3 empty 2.92 67.2 13 No No
4 empty 2.44 61.3 11.5 No No
5 empty 2.43 57.2 11.8 No No
6 empty 3.38 63 5.8 No No
2EOW_A Zinc finger protein 347 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.53 55.7 20.3 No No
2 empty 2.36 46.6 14.5 No No
3 empty 2.3 57.7 12.4 No No
4 empty 2.6 42.4 10.9 No No
5 empty 2.76 56.5 7.4 No No
6 empty 2.9 59.8 6 No No
7 empty 3.2 47.3 6.5 No No
2EQ3_A Zinc finger protein 347 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.5 50.4 18.9 No No
2 empty 2.62 62.9 17.3 No No
3 empty 2.29 51.2 10.5 No No
4 empty 2.85 59.4 8.5 No No
5 empty 2.42 44.1 8.7 No No
2YTN_A Zinc finger protein 347 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.61 58.7 19.5 No No
2 empty 2.18 48.3 9.7 No No
3 empty 2.65 60.2 9.6 No No
4 empty 2.61 52.6 8.9 No No
5 empty 2.94 54.5 8.1 No No
6 empty 3.02 45.5 6.4 No No
7 empty 2.87 68.2 5.9 No No
2YTK_A Zinc finger protein 347 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.4 59.5 21.1 No No
2 empty 2.46 60.7 14.7 No No
3 empty 2.74 54.3 12.7 No No
4 empty 2.73 56 11.6 No No
5 empty 3.13 54.7 7.5 No No
6 empty 2.81 64.5 7 No No
2EQ1_A Zinc finger protein 347 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.21 49.5 16.3 No No
2 empty 2.59 56.7 12.7 No No
3 empty 2.36 48.1 13.1 No No
4 empty 2.65 66.2 10.7 No No
5 empty 2.73 47.5 7.6 No No
6 empty 3.25 62.1 7.3 No No
7 empty 3.14 52.4 5.5 No No
8 empty 3.24 51.9 6.2 No No
2EQ2_A Zinc finger protein 347 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.4 53.7 14.3 No No
2 empty 2.62 54.3 13.4 No No
3 empty 2.78 50.8 6.7 No No
4 empty 3.16 48 9.4 No No
5 empty 3.11 50.9 7.7 No No
6 empty 1.87 60.2 7.2 No No
7 empty 3.07 47.2 6 No No
8 empty 2.88 63.6 5.1 No No
9 empty 3.22 72.4 5.1 No No
10 empty 2.81 42.3 5.7 No No
2YU8_A Zinc finger protein 347 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.26 47.6 12.5 No No
2 empty 2.97 56 10.9 No No
3 empty 2.33 55.1 11.7 No No
4 empty 2.91 67.6 11.4 No No
5 empty 2.89 54.2 10.6 No No
6 empty 2.86 56 9.2 No No
7 empty 2.42 61.9 7.5 No No
8 empty 2.25 49.4 11 No No
9 empty 2.62 63.2 5.9 No No
10 empty 2.72 42 6.1 No No
2ENE_A Zinc finger protein 347 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.58 48.9 22.9 No No
2 empty 3.06 67.1 16.5 No No
3 empty 2.78 61.9 9.9 No No
4 empty 2.64 50.8 10.8 No No
5 empty 2.81 52.4 7 No No
6 empty 3.11 42.3 7.4 No No
7 empty 3.08 55.8 7.1 No No
8 empty 3.26 53.6 6.9 No No
9 empty 2.56 54.9 6 No No
10 empty 3.59 42.7 5.9 No No
2EMP_A Zinc finger protein 347 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.5 57.8 18.4 No No
2 empty 2.29 58 16.7 No No
3 empty 2.32 51.8 11.3 No No
4 empty 2.46 57.6 6.5 No No
5 empty 3.15 73.4 6.7 No No
6 empty 2.41 59.4 8 No No
7 empty 2.33 61.7 5.8 No No
2EMA_A Zinc finger protein 347 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.57 51.5 16.8 No No
2 empty 2.7 57 9.4 No No
3 empty 3.2 62.8 8.7 No No
4 empty 2.43 45.9 8.4 No No
5 empty 2.26 58.2 6.9 No No
6 empty 2.37 50 6.3 No No
7 empty 2.5 64 6 No No
8 empty 2.05 55.3 7.3 No No
9 empty 2.64 51 5.7 No No
2EOE_A Zinc finger protein 347 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.25 54.4 14.1 No No
2 empty 2.81 52.5 17.1 No No
3 empty 2.96 67.5 9.1 No No
4 empty 3.32 54.2 7.1 No No
5 empty 2.74 66.3 4 No No
2ENF_A Zinc finger protein 347 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.44 47.7 14.5 No No
2 empty 2.47 50.7 13.1 No No
3 empty 2.62 60.9 14.4 No No
4 empty 2.67 65.7 12.9 No No
5 empty 2.29 54.1 9.9 No No
6 empty 2.78 59.4 5.2 No No
7 empty 2.68 53.9 5.9 No No
8 empty 3.2 53.8 5.4 No No
2YTR_A Zinc finger protein 347 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.33 57.3 19.3 No No
2 empty 2.39 63.5 17 No No
3 empty 2.56 59.3 12.4 No No
4 empty 2.99 48 9.7 No No
5 empty 2.71 58.9 7.7 No No
6 empty 2.77 60.9 7.3 No No
7 empty 2.19 68.2 7.4 No No
8 empty 3.16 64 5.5 No No
9 empty 3.15 69.5 0 No No
2EQ0_A Zinc finger protein 347 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.5 49.4 20.5 No No
2 empty 2.47 55.5 13.2 No No
3 empty 2.16 56.9 13.3 No No
4 empty 2.44 45.2 12.9 No No
5 empty 2.62 55.9 5.8 No No
6 empty 3.8 64.1 5.9 No No
7 empty 2.1 60.5 6.4 No No
8 empty 2.95 60.5 5.9 No No
Ligand-based Druggability Score: -3
Ligand-based Druggability Score Percentile: 59%
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score