Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

ZNF347 (Q96SE7) - Overview - Molecular Target Synopsis

Protein


ZNF347, Zinc finger protein 347
UniProt Q96SE7

Also Known as ZN347_HUMAN, ZNF347, ZNF1111

May be involved in transcriptional regulation.

2YTR
SOLUTION STRUCTURE OF THE C2H2 TYPE ZINC FINGER (REGION 760- 792) OF HUMAN ZINC FINGER PROTEIN 347
RCSB/PDB
Inspect Structure
See all 3D Structures for ZNF347

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: ZNF347 is active in the following subcellular-locations: nucleus.
GO terms: ZNF347 is active in the following subcellular-locations: nucleus.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project ZNF347 has gain in 2 cell-lines, loss in 2 cell-lines and no signal in 1001 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: MDA_MB_231, SNB_19, TK_10

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: COV318, NCI-H1882, RT4

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, A549, HMEC

(see details)

3D Structures


For ZNF347 there are:
16 structures (16 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


ZNF347 has been screened with compounds ( bioactivities). (see details)