TSSK2 (Q96PF2) - Overview - Molecular Target Synopsis
TSSK2, Testis-specific serine/threonine-protein kinase 2
Enzyme Classification 220.127.116.11
Also Known as TSSK2_HUMAN, TSSK2, DGSG, SPOGA2, STK22B
Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates TSKS at 'Ser-288' and SPAG16. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body. Interacts with TSSK1B. Interacts with HSP90; this interaction stabilizes TSSK2 (By similarity).
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
UniProt: TSSK2 is active in the following subcellular-locations: centriole, centrosome, cytoplasm, cytoskeleton, microtubule organizing center.
GO terms: TSSK2 is active in the following subcellular-locations: acrosomal vesicle, centriole, cytoplasm, nucleus.