Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

RHOV (Q96L33) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Ras family (100%) (view alignment) CDC42 (P60953) - HUMAN 1AN0_A 57.39 3.0E-56 2.8Å GDP 1999-01-13
Ras family (100%) (view alignment) CDC42 (P60953) ARHGAP1 (Q07960) HUMAN 1AM4_E 56.57 2.0E-55 2.7Å GNP 1998-07-15
Ras family (100%) (view alignment) CDC42 (P60953) WAS (P42768) HUMAN 1CEE_A 57.39 2.0E-56 GCP 1999-06-30
Ras family (100%) (view alignment) RHOA (P61586) ARHGAP1 (Q07960) HUMAN 6R3V_B 44.81 1.0E-41 1.75Å GDP MES 2019-05-08
Ras family (100%) (view alignment) RHOA (P61586) (Q8KNY0) HUMAN 4XSG_A 44.83 7.0E-41 1.8Å GSP 2015-06-24
Ras family (100%) (view alignment) - BRAIN-EATING AMOEBA 5VCU_A 45.86 3.0E-45 1.85Å GDP 2017-05-03
Ras family (100%) (view alignment) RAC1 (P63000), (O49003) - OAT, HUMAN 2WKR_A 54.86 1.0E-54 2.2Å GTP FMN 2009-08-18
Ras family (100%) (view alignment) Cdc42 (P60766) Diaph1 (O08808) MOUSE 3EG5_C 56.82 5.0E-56 2.7Å GNP 2008-10-14
Ras family (100%) (view alignment) CDC42 (P60953) Pak3 (Q61036) HUMAN 1EES_A 57.39 2.0E-56 - 2000-03-29
Ras family (100%) (view alignment) CDC42 (P60953) DOCK7 (Q96N67) HUMAN 6AJ4_F 57.39 2.0E-56 3.256Å - 2019-03-20
Ras family (100%) (view alignment) RHOA (P61586) ARHGDIA (P52565) HUMAN 1CC0_A 44.81 3.0E-41 4Å GDP 2000-01-07
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 3TH5_B 55.68 6.0E-56 2.3Å GNP 2012-07-18
Ras family (100%) (view alignment) CDC42 (P60953) IQGAP2 (Q13576) HUMAN 5CJP_A 56.57 6.0E-55 2.57Å GTP 2016-08-10
Ras family (100%) (view alignment) RHOA (P61586) (Q8KNY0) HUMAN 5BWM_A 44.83 7.0E-41 2.5Å GDP 2015-06-24
Ras family (100%) (view alignment) RAC1 (P63000) Tiam1 (Q60610) HUMAN 1FOE_F 55.68 7.0E-56 2.8Å - 2001-01-17
Ras family (100%) (view alignment) RAC3 (P60763) PAK1 (Q13153) HUMAN 2QME_A 55.68 1.0E-55 1.75Å GCP 2007-08-28
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 2P2L_B 55.11 1.0E-54 1.9Å GDP 2007-05-01
Ras family (100%) (view alignment) RAC2 (P15153) - HUMAN 2W2V_A 53.98 7.0E-54 1.95Å GTP 2009-05-05
Ras family (100%) (view alignment) CDC42 (P60953) - HUMAN 2QRZ_B 57.39 3.0E-56 2.4Å GCP 2008-03-18
Ras family (100%) (view alignment) CDC42 (P60953) Mcf2l (Q64096) HUMAN 1KZ7_B 57.39 2.0E-56 2.4Å - 2002-03-20
Ras family (100%) (view alignment) RHOA (P61586) (Q8KNY0) HUMAN 4XSH_A 44.83 7.0E-41 2.3Å GSP 2015-06-24
Ras family (100%) (view alignment) RAC1 (P63000) ARHGDIA (P52565) HUMAN 1HH4_A 55.11 1.0E-54 2.7Å GDP 2001-08-28
Ras family (100%) (view alignment) RAC1 (P63000) DOCK2 (Q92608) HUMAN 3B13_B 56 8.0E-56 3Å - 2012-03-14
Ras family (100%) (view alignment) RHO1 (P06780) SEC3 (P33332) BAKER'S YEAST 3A58_F 43.26 3.0E-38 2.6Å GNP 2010-01-12
Ras family (100%) (view alignment) RAC3 (P60763) PAK4 (O96013) HUMAN 2OV2_E 55.68 1.0E-55 2.1Å GCP 2007-03-13
Ras family (100%) (view alignment) ARAC7 (O82480) - MOUSE-EAR CRESS 2J0V_A 45.6 4.0E-44 1.78Å GDP 2006-10-04
Ras family (100%) (view alignment) RAC1 (P63000) TRIO (O75962) HUMAN 2NZ8_A 55.68 7.0E-56 2Å - 2007-04-10
Ras family (100%) (view alignment) RAC1 (P63000) PREX1 (Q8TCU6) HUMAN 5FI0_D 55.68 1.0E-55 3.25Å - 2016-04-20
Ras family (100%) (view alignment) RAC1 (P63000) ARHGEF28 (Q8N1W1) HUMAN 6BC1_B 55.68 9.0E-56 2.54Å GSP 2017-12-13
Ras family (100%) (view alignment) RHOA (P61586) ARHGDIA (P19803) HUMAN 5FR1_A 44.81 9.0E-42 2.75Å GDP 2016-01-13
Ras family (100%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 5JHG_F 44.57 1.0E-41 2.5Å - 2017-04-26
Ras family (100%) (view alignment) CDC42 (P60953) Mcf2l (Q64096) HUMAN 1KZG_B 57.39 2.0E-56 2.6Å - 2002-03-20
Ras family (100%) (view alignment) CDC42 (P60953) ITSN1 (Q15811) HUMAN 3QBV_A 57.39 7.0E-56 2.65Å GDP 2012-02-08
Ras family (100%) (view alignment) RAC2 (P15153) ARHGDIB (P52566) HUMAN 1DS6_A 54.55 7.0E-55 2.35Å GDP 2000-07-12
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 4GZM_A 55.68 2.0E-55 2.8Å GSP 2012-12-12
Ras family (100%) (view alignment) CDC42 (P60953) DOCK9 (Q9BZ29) HUMAN 2WMN_B 57.39 3.0E-56 2.39Å GDP 2009-09-22
Ras family (100%) (view alignment) CDC42 (P60953) DOCK7 (Q96N67) HUMAN 6AJL_F 57.39 2.0E-56 3.23Å - 2019-03-20
Ras family (100%) (view alignment) RAC2 (P15153) PLCG2 (P16885) HUMAN 2W2X_B 53.98 1.0E-53 2.3Å GSP 2009-05-05
Ras family (100%) (view alignment) RHOA (P61586) (Q9AJW7) HUMAN 3LWN_B 44.57 2.0E-41 2.28Å GDP 2010-03-31
Ras family (100%) (view alignment) RAC1 (P63000) ARHGEF28 (Q8N1W1) HUMAN 6BC1_A 55.68 9.0E-56 2.54Å GSP 2017-12-13
Ras family (100%) (view alignment) RHOA (P61586) ROCK1 (Q13464) HUMAN 1S1C_B 44.57 1.0E-41 2.6Å GNP 2004-02-10
Ras family (100%) (view alignment) RAC1 (P63000) PREX1 (Q8TCU6) HUMAN 5FI0_F 55.68 1.0E-55 3.25Å - 2016-04-20
Ras family (100%) (view alignment) RHOD (O00212) - HUMAN 2J1L_A 41.67 1.0E-39 2.5Å GDP 2006-09-18
Ras family (100%) (view alignment) CDC42 (P60953) PAK4 (O96013) HUMAN 5UPK_C 56 1.0E-54 2.4Å GNP 2017-12-27
Ras family (100%) (view alignment) CDC42 (P60953) ITSN1 (Q15811) HUMAN 3QBV_C 57.39 7.0E-56 2.65Å GDP 2012-02-08
Ras family (100%) (view alignment) RHOA (P61586) Arhgef18 (Q6P9R4) HUMAN 6BCB_F 44.57 2.0E-41 1.4Å GSP 2017-12-13
Ras family (98%) (view alignment) ARAC5 (Q38937) ROPGEF8 (Q9LV40) THALE CRESS 2NTY_C 49.71 7.0E-46 3.1Å GDP 2007-01-23
Ras family (100%) (view alignment) CDC42 (P60953) TNK2 (Q07912) HUMAN 1CF4_A 56.82 1.0E-55 GNP 1999-06-18
Ras family (100%) (view alignment) RHOA (P61586) ARHGDIA (P52565) HUMAN 1CC0_C 44.81 3.0E-41 4Å GDP 2000-01-07
Ras family (100%) (view alignment) RAC2 (P15153) PLCG2 (P16885) HUMAN 2W2X_A 53.98 1.0E-53 2.3Å GSP 2009-05-05
Ras family (100%) (view alignment) RAC3 (P60763) PAK4 (O96013) HUMAN 2OV2_G 55.68 1.0E-55 2.1Å GCP 2007-03-13
Ras family (100%) (view alignment) ARAC7 (O82480) - MOUSE-EAR CRESS 2J0V_D 45.6 4.0E-44 1.78Å GDP 2006-10-04
Ras family (100%) (view alignment) CDC42 (P60953) - HUMAN 1A4R_A 56.82 3.0E-55 2.5Å GDP 1999-03-02
Ras family (100%) (view alignment) RHOA (P61586) (Q9AJW7) HUMAN 3LW8_B 44.57 2.0E-41 1.85Å GDP 2010-03-31
Ras family (100%) (view alignment) RHOC (P08134) - HUMAN 2GCN_A 44.57 2.0E-41 1.85Å GDP 2007-03-27
Ras family (100%) (view alignment) CDC42 (P60953) DOCK7 (Q96N67) HUMAN 6AJ4_B 57.39 2.0E-56 3.256Å - 2019-03-20
Ras family (100%) (view alignment) RHOA (P61586) RAP1GDS1 (P52306) HUMAN 5ZHX_g 44.81 1.0E-41 3.5Å FAR 2018-09-05
Ras family (100%) (view alignment) CDC42 (P60953) ARHGAP1 (Q07960) HUMAN 2NGR_A 57.39 3.0E-56 1.9Å GDP 1999-01-06
Ras family (100%) (view alignment) RAC1 (P63000) sptP (P74873) HUMAN 1G4U_R 55.11 1.0E-54 2.3Å GDP 2001-01-24
Ras family (100%) (view alignment) RHOC (P08134) Diaph1 (O08808) HUMAN 1Z2C_C 44.57 7.0E-41 3Å GNP 2005-05-10
Ras family (100%) (view alignment) RHOU (Q7L0Q8) - HUMAN 2Q3H_A 67.23 2.0E-68 1.73Å GDP 2007-06-19
Ras family (100%) (view alignment) RHOA (P61586) ARHGAP1 (Q07960) HUMAN 5M6X_B 44.81 4.0E-41 2.4Å GDP 2017-05-17
Ras family (100%) (view alignment) RHOA (P61586) (Q9AJW7) HUMAN 3LW8_C 44.57 2.0E-41 1.85Å GDP 2010-03-31
Ras family (100%) (view alignment) CDC42 (P60953) ARHGAP1 (Q07960) HUMAN 1GRN_A 57.39 3.0E-56 1.8Å GDP 1999-12-22
Ras family (100%) (view alignment) RHOA (P61586) (Q9AJW7) HUMAN 3LXR_A 44.57 2.0E-41 1.68Å GDP 2010-03-31
Ras family (100%) (view alignment) CDC42 (P60953) sopE (O52623) 1GZS_A 57.39 2.0E-56 2.3Å - 2002-09-12
Ras family (100%) (view alignment) RHOA (P61586) MYO9B (Q13459) HUMAN 5HPY_B 44.57 6.0E-41 2.4Å GDP 2016-07-13
Ras family (100%) (view alignment) Rhoa (P61589) - RAT 3TVD_B 44.81 9.0E-42 2.989Å GSP 2012-10-10
Ras family (100%) (view alignment) RHOA (P61586) (Q9AJW7) HUMAN 3LW8_A 44.57 2.0E-41 1.85Å GDP 2010-03-31
Ras family (100%) (view alignment) RHOA (P61586) ARHGEF12 (Q9NZN5) HUMAN 1X86_F 44.81 9.0E-42 3.2Å - 2004-09-21
Ras family (100%) (view alignment) RHOA (P61586) ARHGAP20 (Q9P2F6) HUMAN 3MSX_A 44.57 5.0E-41 1.65Å GDP 2011-03-16
Ras family (100%) (view alignment) RHOA (P61586) Gnaq (P21279), Gnai1 (P10824), ARHGEF25 (Q86VW2) HUMAN 2RGN_F 44.81 9.0E-42 3.5Å - 2008-01-15
Ras family (100%) (view alignment) RAC1 (P63000) PLXNB1 (O43157) HUMAN 3SUA_A 55.37 5.0E-56 4.39Å GNP 2011-09-07
Ras family (100%) (view alignment) CDC42 (P60953) ibpA (Q06277) HUMAN 4ITR_D 57.39 3.0E-56 2.3Å GDP AMP 2013-02-20
Ras family (100%) (view alignment) RHOA (P61586) ARHGEF28 (Q8N1W1) HUMAN 6BC0_F 44.57 2.0E-41 2.198Å GSP 2017-12-13
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 3SBE_A 55.11 5.0E-55 2.6Å GNP 2012-07-18
Ras family (100%) (view alignment) RHOA (P61586) ARHGEF12 (Q9NZN5) HUMAN 1X86_H 44.81 9.0E-42 3.2Å - 2004-09-21
Ras family (100%) (view alignment) RHOA (P61586) ARHGAP1 (Q07960) HUMAN 5M70_B 44.81 4.0E-41 2.2Å GDP 2017-05-17
Ras family (100%) (view alignment) RHOA (P61586) ROCK1 (Q13464) HUMAN 1S1C_A 44.57 1.0E-41 2.6Å GNP 2004-02-10
Ras family (100%) (view alignment) RAC3 (P60763) PAK4 (O96013) HUMAN 2OV2_A 55.68 1.0E-55 2.1Å GCP 2007-03-13
Ras family (100%) (view alignment) CDC42 (P60953) FMNL1 (O95466) HUMAN 4YDH_D 56.82 6.0E-56 3.8Å GNP 2015-05-13
Ras family (100%) (view alignment) RAC1 (P63000), (O49003) - OAT, HUMAN 2WKQ_A 54.86 1.0E-54 1.6Å GTP FMN 2009-08-18
Ras family (100%) (view alignment) RHOA (P61586) ARHGAP1 (Q07960) HUMAN 1OW3_B 44.81 3.0E-41 1.8Å GDP 2003-05-06
Ras family (100%) (view alignment) RAC3 (P60763) PAK4 (O96013) HUMAN 2OV2_B 55.68 1.0E-55 2.1Å GCP 2007-03-13
Ras family (100%) (view alignment) CDC42 (P60953) FMNL2 (Q96PY5) HUMAN 4YC7_A 56.82 6.0E-56 2.5Å GNP 2015-05-13
Ras family (100%) (view alignment) RHOA (P61586) ARHGEF12 (Q9NZN5) HUMAN 1X86_B 44.81 9.0E-42 3.2Å - 2004-09-21
Ras family (100%) (view alignment) RAC1 (P63000) DOCK2 (Q92608) HUMAN 3B13_D 56 8.0E-56 3Å - 2012-03-14
Ras family (100%) (view alignment) RAC1 (P63000) Vav1 (P27870) HUMAN 2VRW_A 55.68 1.0E-55 1.85Å - 2008-06-17
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 5N6O_B 55.68 7.0E-56 2.586Å GDP 2017-12-27
Ras family (100%) (view alignment) CDC42 (P60953) ITSN1 (Q15811) HUMAN 1KI1_C 57.39 2.0E-56 2.3Å - 2002-05-29
Ras family (100%) (view alignment) CDC42 (P60953) DOCK7 (Q96N67) HUMAN 6AJ4_H 57.39 2.0E-56 3.256Å - 2019-03-20
Ras family (100%) (view alignment) RHOA (P61586) - HUMAN 1DPF_A 44 1.0E-40 1.9Å GDP 2000-06-21
Ras family (100%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 3KZ1_F 44.57 1.0E-41 2.7Å GSP 2010-04-28
Ras family (100%) (view alignment) CDC42 (P60953) FMNL1 (O95466) HUMAN 4YDH_B 56.82 6.0E-56 3.8Å GNP 2015-05-13
Ras family (100%) (view alignment) RHOQ (P17081) - HUMAN 2ATX_A 55.37 3.0E-53 2.65Å GNP 2005-09-13
Ras family (100%) (view alignment) RHOA (P61586) Arhgap35 (P81128) HUMAN 5IRC_D 44.57 5.0E-41 1.72Å CSX GDP 2016-08-17
Ras family (100%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 5JHH_F 44.57 1.0E-41 2.3Å RA0 2017-04-26
Ras family (100%) (view alignment) CDC42 (P60953) IQGAP2 (Q13576) HUMAN 5CJP_D 56.57 6.0E-55 2.57Å GTP 2016-08-10
Ras family (100%) (view alignment) CDC42 (P60953) ITSN1 (Q15811), (O49003) HUMAN 5HZK_A 56.82 5.0E-56 3.3Å GDP 2016-12-21
Ras family (100%) (view alignment) RAC3 (P60763) PAK4 (O96013) HUMAN 2OV2_D 55.68 1.0E-55 2.1Å GCP 2007-03-13
Ras family (100%) (view alignment) - BRAIN-EATING AMOEBA 5VCU_B 45.86 3.0E-45 1.85Å GDP 2017-05-03
Ras family (100%) (view alignment) CDC42 (P60953) Mcf2l (Q64096) HUMAN 1KZG_D 57.39 2.0E-56 2.6Å - 2002-03-20
Ras family (100%) (view alignment) RAC1 (P63000) ypkA (Q05608) HUMAN 2H7V_A 55.11 1.0E-54 2.6Å GDP 2006-09-19
Ras family (100%) (view alignment) RAC1 (P63000) VAV1 (P15498) HUMAN 3BJI_C 55.68 7.0E-56 2.6Å - 2008-07-15
Ras family (100%) (view alignment) RAC3 (P60763) - HUMAN 2C2H_B 55.68 2.0E-55 1.8Å GDP 2005-10-13
Ras family (100%) (view alignment) RAC1 (P63000) PREX1 (Q8TCU6) HUMAN 5FI0_B 55.68 1.0E-55 3.25Å - 2016-04-20
Ras family (100%) (view alignment) CDC42 (P60953) - HUMAN 2KB0_A 56.82 8.0E-56 - 2009-12-01
Ras family (100%) (view alignment) ARAP3 (Q8WWN8), RHOA (P61586) - HUMAN 5JCP_B 44.57 4.0E-41 2.1Å GDP 2016-06-22
Ras family (100%) (view alignment) RAC3 (P60763) - HUMAN 2G0N_B 55.68 1.0E-55 1.9Å GDP 2006-05-30
Ras family (100%) (view alignment) RAC2 (P15153) - HUMAN 2W2T_A 53.98 1.0E-53 1.95Å GDP 2009-05-05
Ras family (100%) (view alignment) RHOA (P61586) MYO9B (Q13459) HUMAN 5HPY_F 44.57 6.0E-41 2.4Å GDP 2016-07-13
Ras family (98%) (view alignment) ARAC6 (Q9SBJ6) - THALE CRESS 3BWD_D 49.71 8.0E-46 1.53Å GDP 2008-03-11
Ras family (100%) (view alignment) CDC42 (P60953) Pard6b (Q9JK83) HUMAN 1NF3_B 56.82 2.0E-55 2.1Å GNP 2003-03-04
Ras family (100%) (view alignment) RHOA (P61586) - HUMAN 1KMQ_A 44 4.0E-40 1.55Å GNP 2003-05-06
Ras family (100%) (view alignment) RAC1 (P63000) DOCK2 (Q92608) HUMAN 2YIN_D 55.68 5.0E-56 2.7Å - 2011-05-25
Ras family (100%) (view alignment) RHOA (P61586) - HUMAN 1FTN_A 44.81 3.0E-41 2.08Å GDP 1998-03-18
Ras family (100%) (view alignment) RHOC (P08134) - HUMAN 2GCO_B 44.57 2.0E-41 1.4Å GNP 2007-03-27
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 1RYF_A 50.26 3.0E-52 1.75Å GDP 2004-01-27
Ras family (100%) (view alignment) CDC42 (P60953) - HUMAN 1A4R_B 56.82 3.0E-55 2.5Å GNH 1999-03-02
Ras family (100%) (view alignment) CDC42 (P60953) ARHGAP1 (Q07960) HUMAN 1AM4_F 56.57 2.0E-55 2.7Å GNP 1998-07-15
Ras family (100%) (view alignment) RAC2 (P15153) - HUMAN 2W2V_D 53.98 7.0E-54 1.95Å GTP 2009-05-05
Ras family (100%) (view alignment) RHOA (P61586) RAP1GDS1 (P52306) HUMAN 5ZHX_e 44.81 1.0E-41 3.5Å FAR 2018-09-05
Ras family (100%) (view alignment) RAC1 (P63000) PLCB2 (Q00722) HUMAN 2FJU_A 55.68 7.0E-56 2.2Å GSP 2006-11-21
Ras family (100%) (view alignment) RHOA (P61586) ARHGEF12 (Q9NZN5) HUMAN 1X86_D 44.81 9.0E-42 3.2Å - 2004-09-21
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 1RYH_A 50.26 3.0E-52 1.75Å GNP 2004-01-27
Ras family (100%) (view alignment) CDC42 (P60953) DOCK7 (Q96N67) HUMAN 6AJ4_D 57.39 2.0E-56 3.256Å - 2019-03-20
Ras family (100%) (view alignment) RHOA (P61586) ARHGDIA (P19803) HUMAN 5FR2_A 44.81 9.0E-42 3.35Å FAR GDP 2016-01-13
Ras family (100%) (view alignment) RACGAP1 (Q9H0H5), RHOA (P61586) - HUMAN 5C2K_A 44.81 7.0E-42 1.42Å GDP 2016-06-22
Ras family (100%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 3T06_B 44.57 5.0E-41 2.84Å - 2011-08-03
Ras family (100%) (view alignment) Rhoa (Q9QUI0) Arhgdia (Q99PT1) MOUSE 4F38_A 44.81 8.0E-42 2.8Å GNP GER 2012-05-23
Ras family (100%) (view alignment) CDC42 (P60953) ARHGAP1 (Q07960) HUMAN 1AM4_D 56.57 2.0E-55 2.7Å GNP 1998-07-15
Ras family (100%) (view alignment) RAC1 (P63000) ARFIP2 (P53365) HUMAN 1I4D_D 55.68 1.0E-55 2.5Å GDP 2001-05-16
Ras family (100%) (view alignment) RAC3 (P60763) PAK4 (O96013) HUMAN 2OV2_F 55.68 1.0E-55 2.1Å GCP 2007-03-13
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 5N6O_A 55.68 7.0E-56 2.586Å GDP 2017-12-27
Ras family (100%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 5JHH_B 44.57 1.0E-41 2.3Å RA0 2017-04-26
Ras family (100%) (view alignment) RHOA (P61586) ARHGAP1 (Q07960) HUMAN 5M70_G 44.81 4.0E-41 2.2Å GDP 2017-05-17
Ras family (100%) (view alignment) CDC42 (P60953) DOCK9 (Q9BZ29) HUMAN 2WMO_B 57.39 3.0E-56 2.2Å GTP 2009-09-22
Ras family (100%) (view alignment) RHO1 (P06780) SEC3 (P33332) BAKER'S YEAST 3A58_D 43.26 3.0E-38 2.6Å GNP 2010-01-12
Ras family (100%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 3T06_F 44.57 5.0E-41 2.84Å - 2011-08-03
Ras family (100%) (view alignment) RAC1 (P63000) NCF2 (P19878) HUMAN 1E96_A 55.11 9.0E-55 2.4Å GTP 2000-11-17
Ras family (100%) (view alignment) CDC42 (P60953) - HUMAN 2QRZ_A 57.39 3.0E-56 2.4Å GCP 2008-03-18
Ras family (100%) (view alignment) RAC1 (P63000) Plxna1 (P70206) HUMAN 3RYT_C 55.11 5.0E-55 3.58Å GNP 2012-01-18
Ras family (100%) (view alignment) CDC42 (P60953) PAK4 (O96013) HUMAN 5UPL_B 57.14 9.0E-56 3Å - 2017-12-27
Ras family (100%) (view alignment) RHOA (P61586) ANLN (Q9NQW6) HUMAN 4XOI_A 44 4.0E-40 2.09Å GTP 2015-07-15
Ras family (100%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 5JHG_B 44.57 1.0E-41 2.5Å - 2017-04-26
Ras family (100%) (view alignment) CDC42 (P60953) Mcf2l (Q64096) HUMAN 1KZ7_D 57.39 2.0E-56 2.4Å - 2002-03-20
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 4GZL_B 55.11 4.0E-55 2Å GNP 2012-12-12
Ras family (100%) (view alignment) RAC1 (P63000) PREX1 (Q8TCU6) HUMAN 4YON_B 55.11 7.0E-55 1.95Å - 2015-07-01
Ras family (100%) (view alignment) RAC1 (P63000), (O49003) - OAT, HUMAN 2WKP_A 54.86 2.0E-54 1.9Å GTP FMN 2009-08-18
Ras family (100%) (view alignment) RHOA (P61586) ANLN (Q9NQW6) HUMAN 4XOI_C 44 4.0E-40 2.09Å GTP 2015-07-15
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 4GZL_A 55.11 4.0E-55 2Å GNP 2012-12-12
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 3TH5_A 55.68 6.0E-56 2.3Å GNP 2012-07-18
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 1MH1_A 55.11 1.0E-54 1.38Å GNP 1998-01-21
Ras family (100%) (view alignment) RAC1 (P63000) VAV1 (P15498) HUMAN 3BJI_D 55.68 7.0E-56 2.6Å - 2008-07-15
Ras family (100%) (view alignment) RHOC (P08134) - HUMAN 2GCO_A 44.57 2.0E-41 1.4Å CSX GNP 2007-03-27
Ras family (100%) (view alignment) CDC42 (P60953) sopB (O30916) HUMAN 4DID_A 57.39 2.0E-56 2.35Å GDP 2012-02-29
Ras family (100%) (view alignment) RAC1 (P63000) PLXNB1 (O43157) HUMAN 3SUA_C 55.37 5.0E-56 4.39Å GNP 2011-09-07
Ras family (100%) (view alignment) RHOA (P61586) (Q9AJW7) HUMAN 3LWN_A 44.57 2.0E-41 2.28Å GDP 2010-03-31
Ras family (100%) (view alignment) RAC2 (P15153) - HUMAN 2W2V_B 53.98 7.0E-54 1.95Å GTP 2009-05-05
Ras family (100%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 1XCG_B 44.57 5.0E-41 2.5Å - 2004-12-14
Ras family (100%) (view alignment) RHOA (P61586) Gnaq (P21279), Gnai1 (P10824), ARHGEF25 (Q86VW2) HUMAN 2RGN_C 44.81 9.0E-42 3.5Å - 2008-01-15
Ras family (100%) (view alignment) CDC42 (P60953) Dock8 (Q8C147) HUMAN 3VHL_B 57.39 2.0E-56 2.08Å - 2012-06-20
Ras family (100%) (view alignment) RHOA (P61586) ARHGAP1 (Q07960) HUMAN 1TX4_B 44.83 8.0E-41 1.65Å GDP 1998-09-16
Ras family (100%) (view alignment) CDC42 (P60953) ARHGDIA (P19803) HUMAN 1DOA_A 57.39 3.0E-56 2.6Å GDP GER CMT 2000-02-09
Ras family (100%) (view alignment) RHOA (P61586) - HUMAN 5EZ6_B 44.57 1.0E-41 1.8Å GDP 2016-12-07
Ras family (100%) (view alignment) CDC42 (P60953) Pak1 (P35465) HUMAN 1E0A_A 56.82 1.0E-55 GNP 2000-04-18
Ras family (100%) (view alignment) ARAC7 (O82480) - MOUSE-EAR CRESS 2J0V_B 45.6 4.0E-44 1.78Å GDP 2006-10-04
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 2P2L_C 55.11 1.0E-54 1.9Å GDP 2007-05-01
Ras family (100%) (view alignment) ARAC2 (Q38903) ROPGEF8 (Q9LV40) MOUSE-EAR CRESS 2WBL_D 50.86 3.0E-46 2.9Å - 2009-04-14
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 6AGP_A 54.55 8.0E-53 GDP 2019-03-20
Ras family (100%) (view alignment) RAC3 (P60763) - HUMAN 2C2H_A 55.68 2.0E-55 1.8Å GDP 2005-10-13
Ras family (100%) (view alignment) ARAC7 (O82480) - MOUSE-EAR CRESS 2J0V_C 45.6 4.0E-44 1.78Å GDP 2006-10-04
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 2P2L_A 55.11 1.0E-54 1.9Å GDP 2007-05-01
Ras family (100%) (view alignment) CDC42 (P60953) sopE (O52623) 1GZS_C 57.39 2.0E-56 2.3Å - 2002-09-12
Ras family (100%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 3KZ1_E 44.57 1.0E-41 2.7Å GSP 2010-04-28
Ras family (98%) (view alignment) ARAC5 (Q38937) ROPGEF8 (Q9LV40) THALE CRESS 2NTY_D 49.71 7.0E-46 3.1Å GDP 2007-01-23
Ras family (100%) (view alignment) RHOA (P61586) RAP1GDS1 (P52306) HUMAN 5ZHX_h 44.81 1.0E-41 3.5Å FAR 2018-09-05
Ras family (100%) (view alignment) CDC42 (P60953) (Q9R8E4) HUMAN 3GCG_A 57.39 3.0E-56 2.3Å - 2009-07-21
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 3SBD_A 55.11 5.0E-55 2.1Å GNP 2012-07-18
Ras family (100%) (view alignment) RHOA (P61586) Mcf2l (Q64096) HUMAN 1LB1_D 44.81 8.0E-42 2.81Å - 2002-05-29
Ras family (100%) (view alignment) CDC42 (P60953) Arhgef9 (Q9QX73) HUMAN 2DFK_D 57.39 2.0E-56 2.15Å - 2006-05-02
Ras family (100%) (view alignment) RAC1 (P63000) ARHGDIA (P52565) HUMAN 1HH4_B 55.11 1.0E-54 2.7Å GDP 2001-08-28
Ras family (100%) (view alignment) CDC42 (P60953) DOCK7 (Q96N67) HUMAN 6AJL_H 57.39 2.0E-56 3.23Å - 2019-03-20
Ras family (100%) (view alignment) CDC42 (P60953) ITSN1 (Q15811) HUMAN 1KI1_A 57.39 2.0E-56 2.3Å - 2002-05-29
Ras family (100%) (view alignment) CDC42 (P60953) IQGAP2 (Q13576) HUMAN 5CJP_B 56.57 6.0E-55 2.57Å GTP 2016-08-10
Ras family (100%) (view alignment) RHOA (P61586) Mcf2l (Q64096) HUMAN 1LB1_B 44.81 8.0E-42 2.81Å - 2002-05-29
Ras family (100%) (view alignment) RHOC (P08134) Diaph1 (O08808) HUMAN 1Z2C_A 44.57 7.0E-41 3Å GNP 2005-05-10
Ras family (100%) (view alignment) RHOA (P61586) AKAP13 (Q12802) HUMAN 4D0N_A 44.07 1.0E-41 2.1Å GDP 2014-05-21
Ras family (100%) (view alignment) RHOB (P62745) - HUMAN 2FV8_A 45.2 3.0E-42 1.9Å GDP 2006-02-28
Ras family (100%) (view alignment) CDC42 (P60953) PAK6 (Q9NQU5) HUMAN 2ODB_A 57.39 2.0E-56 2.4Å GCP 2007-01-30
Ras family (98%) (view alignment) RAC1 (P63000) (Q51451) HUMAN 1HE1_D 56.98 1.0E-55 2Å GDP 2001-01-02
Ras family (100%) (view alignment) RAC1 (P63000) ARFIP2 (P53365) HUMAN 1I4L_D 55.68 1.0E-55 2.7Å GDP 2001-05-16
Ras family (100%) (view alignment) RAC1 (P63000) PREX1 (Q8TCU6) HUMAN 5FI0_H 55.68 1.0E-55 3.25Å - 2016-04-20
Ras family (98%) (view alignment) RAC1 (Q9SSX0) - RICE 4U5X_A 47.37 6.0E-42 1.9Å GNP 2014-08-20
Ras family (100%) (view alignment) RAC3 (P60763) - HUMAN 2IC5_A 55.68 1.0E-55 1.9Å BTB GNP 2006-10-10
Ras family (100%) (view alignment) CDC42 (P60953) - HUMAN 2ASE_A 57.39 7.0E-56 - 2006-02-21
Ras family (100%) (view alignment) ARAP3 (Q8WWN8), RHOA (P61586) - HUMAN 5JCP_A 44.57 4.0E-41 2.1Å GDP 2016-06-22
Ras family (100%) (view alignment) RHOA (P61586) PKN1 (Q16512) HUMAN 1CXZ_A 44 2.0E-40 2.2Å GSP 1999-10-08
Ras family (100%) (view alignment) RAC1 (P63000) PLXNB1 (O43157) HUMAN 3SU8_A 55.37 5.0E-56 3.2Å GNP 2011-09-28
Ras family (100%) (view alignment) RHOA (P61586) Mcf2l (Q64096) HUMAN 1LB1_H 44.81 8.0E-42 2.81Å - 2002-05-29
Ras family (100%) (view alignment) RHOA (P61586) - HUMAN 5A0F_A 44.57 1.0E-41 2Å NDG GDP 2015-07-22
Ras family (100%) (view alignment) RHOA (P61586) ARHGAP1 (Q07960) HUMAN 5M6X_I 44.81 4.0E-41 2.4Å GDP 2017-05-17
Ras family (100%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 1XCG_F 44.57 5.0E-41 2.5Å - 2004-12-14
Ras family (98%) (view alignment) RAC1 (P63000) (Q51451) HUMAN 1HE1_C 56.98 1.0E-55 2Å GDP 2001-01-02
Ras family (100%) (view alignment) RHOC (P08134) - HUMAN 2GCP_A 44.57 2.0E-41 2.15Å GSP 2007-03-27
Ras family (100%) (view alignment) CDC42 (P60953) ITSN1 (Q15811), (O49003) HUMAN 5HZK_C 56.82 5.0E-56 3.3Å GDP 2016-12-21
Ras family (100%) (view alignment) CDC42 (P60953) ibpA (Q06277) HUMAN 4ITR_C 57.39 3.0E-56 2.3Å GDP AMP 2013-02-20
Ras family (100%) (view alignment) RAC1 (P63000) ypkA (Q05608) HUMAN 2H7V_B 55.11 1.0E-54 2.6Å GDP 2006-09-19
Ras family (100%) (view alignment) ARAC2 (Q38903) ROPGEF8 (Q9LV40) MOUSE-EAR CRESS 2WBL_C 50.86 3.0E-46 2.9Å - 2009-04-14
Ras family (100%) (view alignment) RHOQ (P17081) - HUMAN 2ATX_B 55.37 3.0E-53 2.65Å GNP 2005-09-13
Ras family (100%) (view alignment) RHOA (P61586) AKAP13 (Q12802) HUMAN 6BCA_C 44.57 2.0E-41 1.995Å GSP 2017-12-13
Ras family (100%) (view alignment) RAC1 (P63000) Tiam1 (Q60610) HUMAN 1FOE_B 55.68 7.0E-56 2.8Å - 2001-01-17
Ras family (100%) (view alignment) CDC42 (P60953) - HUMAN 1AJE_A 57.39 2.0E-56 - 1997-11-12
Ras family (100%) (view alignment) CDC42 (P60953) Arhgef9 (Q9QX73) HUMAN 2DFK_B 57.39 2.0E-56 2.15Å - 2006-05-02
Ras family (100%) (view alignment) RAC2 (P15153) - HUMAN 2W2V_C 53.98 7.0E-54 1.95Å GTP 2009-05-05
Ras family (100%) (view alignment) RHOA (P61586) NET1 (Q7Z628) HUMAN 4XH9_B 44.57 6.0E-41 2Å - 2015-01-14
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 3SBD_B 55.11 5.0E-55 2.1Å GNP 2012-07-18
Ras family (100%) (view alignment) CDC42 (P60953) IQGAP2 (Q13576) HUMAN 5CJP_C 56.57 6.0E-55 2.57Å GTP 2016-08-10
Ras family (100%) (view alignment) Rhoa (P61589) - RAT 3TVD_A 44.81 9.0E-42 2.989Å GSP 2012-10-10
Ras family (100%) (view alignment) RAC1 (P63000) DOCK2 (Q92608) HUMAN 2YIN_C 55.68 5.0E-56 2.7Å - 2011-05-25
Ras family (100%) (view alignment) CDC42 (P60953) Pard6b (Q9JK83) HUMAN 1NF3_A 56.82 2.0E-55 2.1Å GNP 2003-03-04
Ras family (100%) (view alignment) RAC1 (P63000) Tiam1 (Q60610) HUMAN 1FOE_D 55.68 7.0E-56 2.8Å - 2001-01-17
Ras family (100%) (view alignment) CDC42 (P60953) DOCK9 (Q9BZ29) HUMAN 2WM9_B 57.39 3.0E-56 2.2Å - 2009-09-22
Ras family (100%) (view alignment) RHOA (P61586) Arhgap35 (P81128) HUMAN 5IRC_F 44.57 5.0E-41 1.72Å CSX GDP 2016-08-17
Ras family (100%) (view alignment) RHOA (P61586) (Q9AJW7) HUMAN 3LW8_D 44.57 2.0E-41 1.85Å GDP 2010-03-31
Ras family (100%) (view alignment) CDC42 (P60953) DOCK7 (Q96N67) HUMAN 6AJL_B 57.39 2.0E-56 3.23Å - 2019-03-20
Ras family (100%) (view alignment) RAC1 (P63000) PKN1 (Q16512) HUMAN 2RMK_A 55.11 6.0E-55 GCP 2007-11-13
Ras family (100%) (view alignment) RAC3 (P60763) PAK4 (O96013) HUMAN 2OV2_C 55.68 1.0E-55 2.1Å GCP 2007-03-13
Ras family (100%) (view alignment) RHOA (P61586) AKAP13 (Q12802) HUMAN 6BCA_F 44.57 2.0E-41 1.995Å GSP 2017-12-13
Ras family (100%) (view alignment) RHOA (P61586) - HUMAN 1A2B_A 44 2.0E-40 2.4Å GSP 1998-06-17
Ras family (100%) (view alignment) CDC42 (P60953) - HUMAN 1AN0_B 57.39 3.0E-56 2.8Å GDP 1999-01-13
Ras family (100%) (view alignment) CDC42 (P60953) BAIAP2 (Q9UQB8) HUMAN 4JS0_A 56.82 2.0E-55 1.9Å PE4 GNP 2014-03-05
Ras family (100%) (view alignment) RAC1 (P63000) Tiam1 (Q60610) HUMAN 1FOE_H 55.68 7.0E-56 2.8Å - 2001-01-17
Ras family (100%) (view alignment) RHOA (P61586) RAP1GDS1 (P52306) HUMAN 5ZHX_f 44.81 1.0E-41 3.5Å FAR 2018-09-05
Ras family (100%) (view alignment) RHOA (P61586) - HUMAN 5C4M_A 44.81 3.0E-41 1.3Å GDP 2016-06-29
Ras family (100%) (view alignment) RAC1 (P63000) Kalrn (P97924) HUMAN 5O33_A 55.68 7.0E-56 1.64Å GDP 2017-05-31
Ras family (100%) (view alignment) RAC3 (P60763) PAK4 (O96013) HUMAN 2OV2_H 55.68 1.0E-55 2.1Å GCP 2007-03-13
Ras family (100%) (view alignment) RAC1 (P63000) PLXNB1 (O43157) HUMAN 3SUA_B 55.37 5.0E-56 4.39Å GNP 2011-09-07
Ras family (100%) (view alignment) Cdc42 (P60766) Diaph1 (O08808) MOUSE 3EG5_A 56.82 5.0E-56 2.7Å GNP 2008-10-14
Ras family (100%) (view alignment) RHOA (P61586) Mcf2l (Q64096) HUMAN 1LB1_F 44.81 8.0E-42 2.81Å - 2002-05-29
Ras family (100%) (view alignment) CDC42 (P60953) PREX1 (Q8TCU6) HUMAN 5FI1_B 57.39 3.0E-56 3.16Å - 2016-04-20
Ras family (100%) (view alignment) RAC3 (P60763) - HUMAN 2IC5_B 55.68 1.0E-55 1.9Å GDP 2006-10-10
Ras family (100%) (view alignment) RHOA (P61586) NET1 (Q7Z628) HUMAN 4XH9_E 44.57 6.0E-41 2Å - 2015-01-14
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 4GZM_B 55.68 2.0E-55 2.8Å GSP 2012-12-12
Ras family (100%) (view alignment) CDC42 (P60953) DOCK7 (Q96N67) HUMAN 6AJL_D 57.39 2.0E-56 3.23Å - 2019-03-20
Ras family (100%) (view alignment) RAC1 (P63000) ARFIP2 (P53365) HUMAN 1I4T_D 55.11 6.0E-55 2.6Å GNP 2001-05-16
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 1RYH_B 50.26 3.0E-52 1.75Å GNP 2004-01-27
Ras family (100%) (view alignment) Cdc42 (P60766) RACGAP1 (Q9H0H5) MOUSE 5C2J_B 57.39 3.0E-56 2.5Å GDP 2016-06-22
Ras family (100%) (view alignment) RAC3 (P60763) - HUMAN 2G0N_A 55.68 1.0E-55 1.9Å GDP 2006-05-30
Ras family (100%) (view alignment) RAC1 (P63000) - HUMAN 1RYF_B 50.26 3.0E-52 1.75Å GDP 2004-01-27