MAML3 (Q96JK9) - Overview - Molecular Target Synopsis
MAML3, Mastermind-like protein 3
Also Known as MAML3_HUMAN, MAML3, KIAA1816
Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Interacts through its N-terminal region with the ankyrin repeat region of the Notch proteins NOTCH1, NOTCH2, NOTCH3 and NOTCH4. Forms a DNA-binding complex with Notch proteins and RBPSUH/RBP-J kappa.
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
UniProt: MAML3 is active in the following subcellular-locations: nucleus speckle.
GO terms: MAML3 is active in the following subcellular-locations: nuclear speck, nucleoplasm, nucleus.