Molecular Target Synopsis
Domains and Structures
Drugs and Clinical Candidates
Ligand Efficiency Plot
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
Germline Genetics

ADAT3 (Q96EY9) - Overview - Molecular Target Synopsis


ADAT3, Probable inactive tRNA-specific adenosine deaminase-like protein 3
UniProt Q96EY9

Also Known as ADAT3_HUMAN, ADAT3, TAD3

Isoforms / Transcripts (Protein Coding)

Sub-cellular localization

GO terms: ADAT3 is active in the following subcellular-locations: nucleoplasm, tRNA-specific adenosine-34 deaminase complex.

GO terms

Gene Copy Number Variation

In COSMIC - Cell Lines Project ADAT3 has gain in 0 cell-lines, loss in 5 cell-lines and no signal in 1000 cell-lines. (see details)

Gene Expression

In NCI60, the highest expressing cell lines are: SR, SK_MEL_28, K_562

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: SNU-398, LXFL529, LNCAP

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: NHLF, HSMM, HMEC

(see details)

3D Structures

At greater than 35% identity similarity to ADAT3 there are:
1 structures (1 chains) solved
0 are solved in complex with at least one small molecule ligand

(see details)
Molecular Target 3D Synopsis