Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

MFSD3 (Q96ES6) - Overview - Molecular Target Synopsis

Protein


MFSD3, Major facilitator superfamily domain-containing protein 3
UniProt Q96ES6

Also Known as MFSD3_HUMAN, MFSD3

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
412ENSG00000167700ENST00000301327ENSP00000301327Q96ES6-1

Sub-cellular localization


UniProt: MFSD3 is active in the following subcellular-locations: membrane.
GO terms: MFSD3 is active in the following subcellular-locations: integral component of membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project MFSD3 has gain in 11 cell-lines, loss in 4 cell-lines and no signal in 986 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: KM12, OVCAR_4, NCI_ADR_RES

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: OVSAHO, NCI-H1781, NCI-H2110

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, K562, A549

(see details)