Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

TATDN2 (Q93075) - Overview - Molecular Target Synopsis

Protein


TATDN2, Putative deoxyribonuclease TATDN2
Enzyme Classification 3.1.21.-
UniProt Q93075

Also Known as TATD2_HUMAN, TATDN2, KIAA0218

Putative deoxyribonuclease.

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
761ENSG00000157014ENST00000287652, ENST00000448281ENSP00000287652, ENSP00000408736Q93075-1
182ENSG00000157014ENST00000426850ENSP00000389896

Sub-cellular localization


UniProt: TATDN2 is active in the following subcellular-locations: nucleus.
GO terms: TATDN2 is active in the following subcellular-locations: cytosol, nuclear speck, nucleoplasm, nucleus.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project TATDN2 has gain in 4 cell-lines, loss in 2 cell-lines and no signal in 999 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: BT_549, MOLT_4, HOP_62

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: BICR 31, RERF-GC-1B, SNU-398

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, HeLa-S3, K562

(see details)