Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

RASL10A (Q92737) - Overview - Molecular Target Synopsis

Protein


RASL10A, Ras-like protein family member 10A
UniProt Q92737

Also Known as RSLAA_HUMAN, RASL10A, RRP22

Potent inhibitor of cellular proliferation.

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
203ENSG00000100276ENST00000216101ENSP00000216101Q92737-1
115ENSG00000100276ENST00000401450ENSP00000386095Q92737-2

Sub-cellular localization


UniProt: RASL10A is active in the following subcellular-locations: cell membrane, nucleolus, nucleus.
GO terms: RASL10A is active in the following subcellular-locations: nucleolus, plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project RASL10A has gain in 0 cell-lines, loss in 2 cell-lines and no signal in 1003 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: OVCAR_5, HS578T, TK_10

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: HCC1171, NCI-H2795, SW 900

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)