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RYR2 (Q92736) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) Ryr2 (E9Q401) - MOUSE 3IM6_A 98.16 3.0E-126 1.7Å - 2009-11-17
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) Ryr2 (E9Q401) - MOUSE 4KEI_A 98.16 3.0E-126 2.4Å - 2013-09-04
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) RYR1 (P11716) - EUROPEAN RABBIT,JAPANESE WHITE RABBIT,DOMESTIC 3ILA_D 77.51 4.0E-93 2.8Å - 2009-11-17
RyR domain (99%) (view alignment) Ryr2 (E9Q401) Prkaca (P05132) MOUSE 6MM8_D 95.22 6.0E-21 1.85Å - 2019-05-08
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) Ryr2 (E9Q401) - MOUSE 3IM7_A 98.16 3.0E-126 2.2Å - 2009-11-17
MIR domain (98%), RIH domain (49%) (view alignment) RYR1 (P11716) - RABBIT 4I96_A 62.62 4.0E-118 2.73Å - 2013-02-20
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (100%), SPRY domain (100%), RyR domain (100%), RyR and IP3R Homology associated (100%), Ryanodine Receptor TM 4-6 (45%), Ion transport protein (100%) (view alignment) RYR1 (P11716) - RABBIT 5J8V_A 75.35 0 4.9Å - 2016-09-14
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (49%) (view alignment) RYR1 (P11716) - RABBIT 4I3N_A 67.88 0 2.95Å - 2013-02-20
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (79%) (view alignment) RYR2 (Q92736) - HUMAN 4JKQ_A 100 0 2.39Å - 2014-04-02
Inositol 1,4,5-trisphosphate/ryanodine receptor (99%) (view alignment) (G8EME3) - DIAMONDBACK MOTH 5Y9V_B 61.82 2.0E-67 2.84Å - 2017-12-20
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) RYR1 (P11716) - EUROPEAN RABBIT,JAPANESE WHITE RABBIT,DOMESTIC 3ILA_F 77.51 4.0E-93 2.8Å - 2009-11-17
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) RYR1 (P11716) - EUROPEAN RABBIT,JAPANESE WHITE RABBIT,DOMESTIC 3ILA_G 77.51 4.0E-93 2.8Å - 2009-11-17
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (47%), SPRY domain (100%), RyR domain (100%) (view alignment) RYR1 (P11716) - RABBIT 4UWA_B 68.25 4.0E-78 6.1Å - 2014-12-10
RyR domain (98%) (view alignment) RYR3 (Q15413) - HUMAN 4ERV_A 60.77 4.0E-22 1.75Å - 2012-06-13
Inositol 1,4,5-trisphosphate/ryanodine receptor (99%) (view alignment) RYR1 (P11716) - RABBIT 3HSM_B 76.42 2.0E-92 2.5Å - 2009-07-28
SPRY domain (100%) (view alignment) Ryr2 (E9Q401) - MOUSE 4P9I_A 98.28 2.0E-103 1.34Å - 2014-11-05
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (47%), SPRY domain (100%), RyR domain (100%) (view alignment) RYR1 (P11716) - RABBIT 4UWE_A 68.25 4.0E-78 8.5Å - 2014-12-10
SPRY domain (100%) (view alignment) RYR1 (P11716) - RABBIT 4P9J_C 64.2 5.0E-73 1.84Å - 2014-11-05
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) RYR1 (P11716) - EUROPEAN RABBIT,JAPANESE WHITE RABBIT,DOMESTIC 3ILA_A 77.51 4.0E-93 2.8Å - 2009-11-17
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (47%), SPRY domain (100%), RyR domain (100%) (view alignment) RYR1 (P11716) - RABBIT 4UWA_A 68.25 4.0E-78 6.1Å - 2014-12-10
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (60%) (view alignment) RYR1 (P11716) - RABBIT 4I6I_A 67.94 0 2.5Å - 2013-02-20
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) Ryr2 (E9Q401) - MOUSE 3QR5_B 82.49 1.0E-100 2.3Å - 2011-06-08
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) RYR1 (P11716) - EUROPEAN RABBIT,JAPANESE WHITE RABBIT,DOMESTIC 3ILA_C 77.51 4.0E-93 2.8Å - 2009-11-17
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (49%) (view alignment) RYR1 (P11716) - RABBIT 4I8M_A 67.88 0 2.8Å - 2013-02-20
RyR domain (99%) (view alignment) RYR1 (P11716) - RABBIT 4ERT_A 63.03 8.0E-23 1.95Å - 2012-06-13
RyR domain (99%) (view alignment) Ryr2 (E9Q401) Prkaca (P05132) MOUSE 6MM7_E 95.22 6.0E-21 1.85Å - 2019-05-08
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (100%), SPRY domain (100%), RyR domain (100%), RyR and IP3R Homology associated (100%), Ryanodine Receptor TM 4-6 (45%), Ion transport protein (100%) (view alignment) RYR1 (P11716) - RABBIT 5J8V_C 75.35 0 4.9Å - 2016-09-14
SPRY domain (100%) (view alignment) RYR1 (P11716) - RABBIT 4P9J_A 64.2 5.0E-73 1.84Å - 2014-11-05
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (47%), SPRY domain (100%), RyR domain (100%) (view alignment) RYR1 (P11716) - RABBIT 4UWE_D 68.25 4.0E-78 8.5Å - 2014-12-10
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) Ryr2 (E9Q401) - MOUSE 4KEJ_A 98.16 2.0E-126 2.55Å - 2013-09-04
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (100%), SPRY domain (100%), RyR domain (100%), RyR and IP3R Homology associated (100%), Ryanodine Receptor TM 4-6 (45%), Ion transport protein (100%) (view alignment) RYR1 (P11716) - RABBIT 5J8V_D 75.35 0 4.9Å - 2016-09-14
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) Ryr2 (E9Q401) - MOUSE 4KEK_A 98.16 2.0E-126 2.146Å - 2013-09-04
Inositol 1,4,5-trisphosphate/ryanodine receptor (99%) (view alignment) (G8EME3) - DIAMONDBACK MOTH 5Y9V_A 61.82 2.0E-67 2.84Å - 2017-12-20
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (60%) (view alignment) RYR1 (P11716) - RABBIT 2XOA_A 68.12 0 2.5Å - 2010-11-10
RyR domain (99%) (view alignment) Ryr2 (E9Q401) - MOUSE 4ETV_A 95.69 5.0E-21 1.65Å - 2012-06-13
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (49%) (view alignment) RYR1 (P11716) - RABBIT 4I37_A 67.88 0 2.95Å - 2013-02-20
RyR domain (99%) (view alignment) Ryr2 (E9Q401) Prkaca (P05132) MOUSE 6MM7_C 95.22 6.0E-21 1.85Å - 2019-05-08
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) RYR1 (P11716) - EUROPEAN RABBIT,JAPANESE WHITE RABBIT,DOMESTIC 3ILA_B 77.51 4.0E-93 2.8Å - 2009-11-17
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (49%) (view alignment) RYR1 (P11716) - RABBIT 4I2S_A 67.88 0 2.5Å - 2013-02-20
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (49%) (view alignment) RYR1 (P11716) - RABBIT 4I1E_A 67.88 0 2.4Å - 2013-02-20
RyR domain (99%) (view alignment) RYR1 (P11716) - RABBIT 4ETT_A 63.03 3.0E-22 2.195Å - 2012-06-13
SPRY domain (100%) (view alignment) Ryr2 (E9Q401) - MOUSE 4P9L_A 97.71 1.0E-103 1.436Å - 2014-11-05
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (47%), SPRY domain (100%), RyR domain (100%) (view alignment) RYR1 (P11716) - RABBIT 4UWA_D 68.25 4.0E-78 6.1Å - 2014-12-10
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) Ryr2 (E9Q401) - MOUSE 3IM5_B 98.62 1.0E-126 2.55Å - 2009-11-17
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (49%) (view alignment) Ryr2 (E9Q401) - MOUSE 4L4I_A 97.44 0 2.15Å - 2013-07-24
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (47%), SPRY domain (100%), RyR domain (100%) (view alignment) RYR1 (P11716) - RABBIT 4UWA_C 68.25 4.0E-78 6.1Å - 2014-12-10
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) RYR1 (P11716) - EUROPEAN RABBIT,JAPANESE WHITE RABBIT,DOMESTIC 3ILA_I 77.51 4.0E-93 2.8Å - 2009-11-17
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) Ryr2 (E9Q401) - MOUSE 3QR5_A 82.49 1.0E-100 2.3Å - 2011-06-08
SPRY domain (100%) (view alignment) RYR1 (P11716) - RABBIT 4P9J_B 64.2 5.0E-73 1.84Å - 2014-11-05
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (47%), SPRY domain (100%), RyR domain (100%) (view alignment) RYR1 (P11716) - RABBIT 4UWE_C 68.25 4.0E-78 8.5Å - 2014-12-10
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (49%) (view alignment) Ryr2 (E9Q401) - MOUSE 4L4H_A 97.62 0 2Å PGE 2013-07-24
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (49%) (view alignment) RYR1 (P11716) - RABBIT 4I7I_A 67.88 0 2.9Å - 2013-02-20
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) Ryr2 (E9Q401) - MOUSE 3IM5_A 98.62 1.0E-126 2.55Å - 2009-11-17
RyR domain (99%) (view alignment) RYR1 (P11716) - RABBIT 4ETU_A 62.56 7.0E-23 2.19Å - 2012-06-13
SPRY domain (100%) (view alignment) Ryr2 (E9Q401) - MOUSE 5VSN_A 97.63 3.0E-99 1.439Å - 2018-05-23
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%) (view alignment) Ryr2 (E9Q401) - MOUSE 2MC2_A 99.07 2.0E-125 - 2013-09-11
RyR domain (99%) (view alignment) RYR1 (P11716) - RABBIT 3RQR_A 63.64 2.0E-22 2.16Å - 2011-06-22
Inositol 1,4,5-trisphosphate/ryanodine receptor (99%) (view alignment) RYR1 (P11716) - RABBIT 3HSM_A 76.42 2.0E-92 2.5Å - 2009-07-28
SPRY domain (100%) (view alignment) Ryr2 (E9Q401) - MOUSE 5C33_B 98.98 2.0E-102 1.21Å - 2015-08-05
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (100%), SPRY domain (100%), RyR domain (100%), RyR and IP3R Homology associated (100%), Ryanodine Receptor TM 4-6 (45%), Ion transport protein (100%) (view alignment) RYR1 (P11716) - RABBIT 5J8V_B 75.35 0 4.9Å - 2016-09-14
SPRY domain (100%) (view alignment) Ryr2 (E9Q401) - MOUSE 5C33_A 98.98 2.0E-102 1.21Å - 2015-08-05
RyR domain (99%) (view alignment) Ryr2 (E9Q401) - MOUSE 4ETV_B 95.69 5.0E-21 1.65Å - 2012-06-13
RyR domain (99%) (view alignment) Ryr2 (E9Q401) Prkaca (P05132) MOUSE 6MM6_F 95.69 5.0E-21 2.39Å - 2019-05-08
RyR domain (99%) (view alignment) RYR1 (P11716) - RABBIT 4ESU_A 63.03 8.0E-23 1.59Å - 2012-06-13
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) RYR1 (P11716) - EUROPEAN RABBIT,JAPANESE WHITE RABBIT,DOMESTIC 3ILA_H 77.51 4.0E-93 2.8Å - 2009-11-17
RyR domain (98%) (view alignment) RYR1 (P11716) - RABBIT 5C30_A 73.23 4.0E-12 1.55Å - 2015-08-05
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (47%), SPRY domain (100%), RyR domain (100%) (view alignment) RYR1 (P11716) - RABBIT 4UWE_B 68.25 4.0E-78 8.5Å - 2014-12-10
Inositol 1,4,5-trisphosphate/ryanodine receptor (100%), MIR domain (100%), RIH domain (49%) (view alignment) RYR1 (P11716) - RABBIT 4I0Y_A 67.88 0 2.8Å - 2013-02-20
RyR domain (99%) (view alignment) Ryr2 (E9Q401) Prkaca (P05132) MOUSE 6MM6_D 95.69 5.0E-21 2.39Å - 2019-05-08
Inositol 1,4,5-trisphosphate/ryanodine receptor (98%) (view alignment) RYR1 (P11716) - EUROPEAN RABBIT,JAPANESE WHITE RABBIT,DOMESTIC 3ILA_E 77.51 4.0E-93 2.8Å - 2009-11-17