Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

MBD3L1 (Q8WWY6) - Overview - Molecular Target Synopsis

Protein


MBD3L1, Methyl-CpG-binding domain protein 3-like 1
UniProt Q8WWY6

Also Known as MB3L1_HUMAN, MBD3L1, MBD3L

Transcriptional repressor.

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
223ENSG00000170948ENST00000305625ENSP00000304198
200ENSG00000170948ENST00000595891ENSP00000471575
194Q8WWY6-1

Sub-cellular localization


UniProt: MBD3L1 is active in the following subcellular-locations: nucleus.
GO terms: MBD3L1 is active in the following subcellular-locations: nucleus.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project MBD3L1 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 1005 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: Hs 746T, NCI-H209, LN-18

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)