Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

APOBEC4 (Q8WW27) - Overview - Molecular Target Synopsis

Protein


APOBEC4, Putative C->U-editing enzyme APOBEC-4
Enzyme Classification 3.5.4.-
UniProt Q8WW27

Also Known as ABEC4_HUMAN, APOBEC4, C1orf169

Putative C to U editing enzyme whose physiological substrate is not yet known.

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
377ENSG00000173627ENST00000308641ENSP00000310622
367Q8WW27-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project APOBEC4 has gain in 0 cell-lines, loss in 2 cell-lines and no signal in 1003 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: Hs 746T, NCI-H209, LN-18

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: GM12878, SK-N-SH, NHLF

(see details)