Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

nop10 (Q8U1R4) - Overview - Molecular Target Synopsis

Protein


nop10, Ribosome biogenesis protein Nop10
UniProt Q8U1R4

Also Known as NOP10_PYRFU, nop10

Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

3MQK
CBF5-NOP10-GAR1 COMPLEX BINDING WITH 17MER RNA CONTAINING ACA TRINUCLEOTIDE
RCSB/PDB
Inspect Structure
See all 3D Structures for nop10

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
60Q8U1R4-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project nop10 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For nop10 there are:
13 structures (14 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis