Molecular Target Synopsis
Domains and Structures
Drugs and Clinical Candidates
Ligand Efficiency Plot
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
Germline Genetics

ABHD11 (Q8NFV4) - Overview - Molecular Target Synopsis


ABHD11, Protein ABHD11
Enzyme Classification 3.-.-.-
UniProt Q8NFV4

Also Known as ABHDB_HUMAN, ABHD11, WBSCR21

Isoforms / Transcripts (Protein Coding)

Sub-cellular localization

GO terms: ABHD11 is active in the following subcellular-locations: mitochondrion.

GO terms

Gene Copy Number Variation

In COSMIC - Cell Lines Project ABHD11 has gain in 1 cell-lines, loss in 3 cell-lines and no signal in 999 cell-lines. (see details)

Gene Expression

In NCI60, the highest expressing cell lines are: HCC_2998, HCT_15, KM12

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: DV-90, OVSAHO, LS 174T

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, A549, HMEC

(see details)

Screening and Chemistry

ABHD11 has been screened with 4 compounds (4 bioactivities), 3 compounds have bioactivities that show binding affinity of <= 500nM (3 bioactivities). (see details)