Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

NSUN7 (Q8NE18) - Overview - Molecular Target Synopsis

Protein


NSUN7, Putative methyltransferase NSUN7
Enzyme Classification 2.1.1.-
UniProt Q8NE18

Also Known as NSUN7_HUMAN, NSUN7

May have S-adenosyl-L-methionine-dependent methyl-transferase activity.

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
718ENSG00000179299ENST00000381782ENSP00000371201Q8NE18-1
475ENSG00000179299ENST00000316607ENSP00000319127Q8NE18-2
277Q8NE18-3

Gene Copy Number Variation


In COSMIC - Cell Lines Project NSUN7 has gain in 1 cell-lines, loss in 3 cell-lines and no signal in 1001 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: NCI_H322M, T47D, TK_10

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: CW-2, Capan-2, NCI-H209

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)