Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

FADS6 (Q8N9I5) - Overview - Molecular Target Synopsis

Protein


FADS6, Fatty acid desaturase 6
Enzyme Classification 1.14.19.-
UniProt Q8N9I5

Also Known as FADS6_HUMAN, FADS6

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
356Q8N9I5-1
350ENSG00000172782ENST00000310226ENSP00000307821
338Q8N9I5-2
219ENSG00000172782ENST00000579663ENSP00000464267

Sub-cellular localization


UniProt: FADS6 is active in the following subcellular-locations: membrane.
GO terms: FADS6 is active in the following subcellular-locations: integral component of membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project FADS6 has gain in 4 cell-lines, loss in 0 cell-lines and no signal in 1001 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: DMS 53, Hs 746T, NCI-H209

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)