Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

PLD5 (Q8N7P1) - Overview - Molecular Target Synopsis

Protein


PLD5, Inactive phospholipase D5
UniProt Q8N7P1

Also Known as PLD5_HUMAN, PLD5

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: PLD5 is active in the following subcellular-locations: membrane.
GO terms: PLD5 is active in the following subcellular-locations: integral component of membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project PLD5 has gain in 1 cell-lines, loss in 0 cell-lines and no signal in 1004 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: Hs 695T, MCF10DCIS.com, NCI-H2081

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)


Screening and Chemistry


PLD5 has been screened with compounds ( bioactivities). (see details)