Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

LIX1 (Q8N485) - Overview - Molecular Target Synopsis

Protein


LIX1, Protein limb expression 1 homolog
UniProt Q8N485

Also Known as LIX1_HUMAN, LIX1, C5orf11

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
282ENSG00000145721ENST00000274382ENSP00000274382Q8N485-1
70ENSG00000145721ENST00000512378ENSP00000427469

Sub-cellular localization


GO terms: LIX1 is active in the following subcellular-locations: cytoplasm.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project LIX1 has gain in 0 cell-lines, loss in 1 cell-lines and no signal in 1004 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: OVCAR_3, OVCAR_4, TK_10

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: OVKATE, OVCAR-4, NIH:OVCAR-3

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)