Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

SLC7A5P1 (Q8MH63) - Overview - Molecular Target Synopsis

Protein


SLC7A5P1, Putative L-type amino acid transporter 1-like protein MLAS
UniProt Q8MH63

Also Known as LAT1N_HUMAN, SLC7A5P1, MLAS

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
180Q8MH63-1

Sub-cellular localization


UniProt: SLC7A5P1 is active in the following subcellular-locations: membrane.
GO terms: SLC7A5P1 is active in the following subcellular-locations: integral component of membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project SLC7A5P1 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: CAL-120, IGR-37, SK-MEL-3

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: GM12878, K562, CD14-positive monocyte

(see details)

3D Structures


At greater than 90% identity similarity to SLC7A5P1 there are:
2 structures (2 chains) solved
2 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


SLC7A5P1 has been screened with compounds ( bioactivities). (see details)