Molecular Target Synopsis
Domains and Structures
Drugs and Clinical Candidates
Ligand Efficiency Plot
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
Germline Genetics

TRMT2A (Q8IZ69) - Overview - Molecular Target Synopsis


TRMT2A, tRNA (uracil-5-)-methyltransferase homolog A
Enzyme Classification 2.1.1.-
UniProt Q8IZ69

Also Known as TRM2A_HUMAN, TRMT2A, HTF9C

May be involved in nucleic acid metabolism and/or modifications.

Isoforms / Transcripts (Protein Coding)

Gene Copy Number Variation

In COSMIC - Cell Lines Project TRMT2A has gain in 11 cell-lines, loss in 1 cell-lines and no signal in 993 cell-lines. (see details)

Gene Expression

In NCI60, the highest expressing cell lines are: K_562, SK_MEL_28, MDA_N

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: HCC515, SNU-182, Hs 294T

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, K562, HUVEC

(see details)