Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

TRMT2A (Q8IZ69) - Overview - Molecular Target Synopsis

Protein


TRMT2A, tRNA (uracil-5-)-methyltransferase homolog A
Enzyme Classification 2.1.1.-
UniProt Q8IZ69

Also Known as TRM2A_HUMAN, TRMT2A, HTF9C

May be involved in nucleic acid metabolism and/or modifications.

Isoforms / Transcripts (Protein Coding)


Gene Copy Number Variation


In COSMIC - Cell Lines Project TRMT2A has gain in 11 cell-lines, loss in 1 cell-lines and no signal in 993 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: K_562, SK_MEL_28, MDA_N

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: HCC515, SNU-182, Hs 294T

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, K562, HUVEC

(see details)