Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

MMD2 (Q8IY49) - Overview - Molecular Target Synopsis

Protein


MMD2, Monocyte to macrophage differentiation factor 2
UniProt Q8IY49

Also Known as PAQRA_HUMAN, MMD2, PAQR10

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: MMD2 is active in the following subcellular-locations: golgi apparatus membrane.
GO terms: MMD2 is active in the following subcellular-locations: Golgi membrane, integral component of membrane, perinuclear region of cytoplasm.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project MMD2 has gain in 8 cell-lines, loss in 2 cell-lines and no signal in 995 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: A549, HCT_116, HOP_92

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: Hs 746T, NCI-H209, LN-18

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)