Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

MFSD6L (Q8IWD5) - Overview - Molecular Target Synopsis

Protein


MFSD6L, Major facilitator superfamily domain-containing protein 6-like
UniProt Q8IWD5

Also Known as MFS6L_HUMAN, MFSD6L

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
663ENSG00000185156ENST00000329805ENSP00000330051
586Q8IWD5-1

Sub-cellular localization


UniProt: MFSD6L is active in the following subcellular-locations: membrane.
GO terms: MFSD6L is active in the following subcellular-locations: integral component of membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project MFSD6L has gain in 1 cell-lines, loss in 8 cell-lines and no signal in 996 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: NCI-H1781, DU4475, HCC2935

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)