Aldh4a1, Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
Enzyme Classification 22.214.171.124
Also Known as
Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes. Homodimer.