Pgp (Q8CHP8) - Overview - Molecular Target Synopsis
Pgp, Glycerol-3-phosphate phosphatase
Enzyme Classification 22.214.171.124
Also Known as PGP_MOUSE, Pgp
Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism (PubMed:26755581). Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear (PubMed:26755581, PubMed:24338473). In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (PubMed:24338473). Homodimer.
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