Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

asbF (Q81RQ4) - Overview - Molecular Target Synopsis

Protein


asbF, 3-dehydroshikimate dehydratase
Enzyme Classification 4.2.1.118
UniProt Q81RQ4

Also Known as ASBF_BACAN, asbF

Converts 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a biosynthetic unit required for the biosynthesis of petrobactin which is a virulence-associated siderophore produced by B.anthracis. Homodimer.

3DX5
CRYSTAL STRUCTURE OF THE PROBABLE 3-DHS DEHYDRATASE ASBF INVOLVED IN THE PETROBACTIN SYNTHESIS FROM BACILLUS ANTHRACIS
RCSB/PDB
Inspect Structure
See all 3D Structures for asbF

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
280Q81RQ4-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project asbF has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For asbF there are:
1 structures (1 chains) solved
1 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis