Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

ERMP1 (Q7Z2K6) - Overview - Molecular Target Synopsis

Protein


ERMP1, Endoplasmic reticulum metallopeptidase 1
Enzyme Classification 3.4.-.-
UniProt Q7Z2K6

Also Known as ERMP1_HUMAN, ERMP1, FXNA, KIAA1815

Within the ovary, required for the organization of somatic cells and oocytes into discrete follicular structures.

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: ERMP1 is active in the following subcellular-locations: endoplasmic reticulum membrane.
GO terms: ERMP1 is active in the following subcellular-locations: endoplasmic reticulum membrane, integral component of membrane, membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project ERMP1 has gain in 12 cell-lines, loss in 15 cell-lines and no signal in 978 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: HT29, COLO205, OVCAR_4

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: KYSE-150, HCC1954, BFTC-909

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: HMEC, HeLa-S3, MCF-7

(see details)