Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

SLC16A9 (Q7RTY1) - Overview - Molecular Target Synopsis

Protein


SLC16A9, Monocarboxylate transporter 9
UniProt Q7RTY1

Also Known as MOT9_HUMAN, SLC16A9, C10orf36, MCT9

Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane.

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
509ENSG00000165449ENST00000395347, ENST00000395348ENSP00000378756, ENSP00000378757Q7RTY1-1

Sub-cellular localization


UniProt: SLC16A9 is active in the following subcellular-locations: cell membrane.
GO terms: SLC16A9 is active in the following subcellular-locations: integral component of plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project SLC16A9 has gain in 6 cell-lines, loss in 0 cell-lines and no signal in 999 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: PC_3, BT_549, 786_0

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: SET-2, NCI-H1869, COLO-704

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HMEC

(see details)


Screening and Chemistry


SLC16A9 has been screened with compounds ( bioactivities). (see details)