Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

SLC16A13 (Q7RTY0) - Overview - Molecular Target Synopsis

Protein


SLC16A13, Monocarboxylate transporter 13
UniProt Q7RTY0

Also Known as MOT13_HUMAN, SLC16A13, MCT13

Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane.

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
426ENSG00000174327ENST00000308027ENSP00000309751Q7RTY0-1

Sub-cellular localization


UniProt: SLC16A13 is active in the following subcellular-locations: cell membrane, golgi apparatus membrane.
GO terms: SLC16A13 is active in the following subcellular-locations: Golgi apparatus, Golgi membrane, integral component of plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project SLC16A13 has gain in 2 cell-lines, loss in 4 cell-lines and no signal in 999 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: H322T, PLC/PRF/5, COLO 205

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: HUVEC, A549, HMEC

(see details)