Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

SLC16A14 (Q7RTX9) - Overview - Molecular Target Synopsis

Protein


SLC16A14, Monocarboxylate transporter 14
UniProt Q7RTX9

Also Known as MOT14_HUMAN, SLC16A14, MCT14

Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane.

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: SLC16A14 is active in the following subcellular-locations: cell membrane.
GO terms: SLC16A14 is active in the following subcellular-locations: integral component of plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project SLC16A14 has gain in 1 cell-lines, loss in 1 cell-lines and no signal in 1003 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: NCI_H460, NCI_H322M, NCI_H522

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: MDA-MB-361, SNU-1, NCI-H1869

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, HSMM, HMEC

(see details)