Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

trmB (Q7LYW4) - Overview - Molecular Target Synopsis

Protein


trmB, HTH-type sugar sensing transcriptional regulator TrmB
UniProt Q7LYW4

Also Known as TRMBR_THELN, trmB

Inhibits transcription of the trehalose/maltose transport gene cluster (malE operon). Acts by binding to two different operator sequences in the promoter, preventing polymerase recruitment and transcription. Homodimer.

2F5T
CRYSTAL STRUCTURE OF THE SUGAR BINDING DOMAIN OF THE ARCHAEAL TRANSCRIPTIONAL REGULATOR TRMB
RCSB/PDB
Inspect Structure
See all 3D Structures for trmB

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform

Gene Copy Number Variation


In COSMIC - Cell Lines Project trmB has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For trmB there are:
1 structures (1 chains) solved
1 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis