Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

truB (Q7LWY0) - Overview - Molecular Target Synopsis

Protein


truB, Probable tRNA pseudouridine synthase B
Enzyme Classification 5.4.99.25
UniProt Q7LWY0

Also Known as TRUB_PYRFU, truB

Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

3MQK
CBF5-NOP10-GAR1 COMPLEX BINDING WITH 17MER RNA CONTAINING ACA TRINUCLEOTIDE
RCSB/PDB
Inspect Structure
See all 3D Structures for truB

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
340Q7LWY0-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project truB has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For truB there are:
13 structures (14 chains) solved
2 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis