Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

virB8 (Q7CEG3) - Overview - Molecular Target Synopsis

Protein


virB8, Type IV secretion system protein virB8
UniProt Q7CEG3

Also Known as VIRB8_BRUSU, virB8

The VirB system could be required for the establishment of the replication niche in the host.

5JBS
CONFORMATIONAL CHANGES DURING MONOMER-TO-DIMER TRANSITION OF BRUCELLA SUIS VIRB8
RCSB/PDB
Inspect Structure
See all 3D Structures for virB8

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform

Sub-cellular localization


UniProt: virB8 is active in the following subcellular-locations: cell inner membrane.
GO terms: virB8 is active in the following subcellular-locations: integral component of membrane, plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project virB8 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For virB8 there are:
4 structures (19 chains) solved
2 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis