Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

MFSD6 (Q6ZSS7) - Overview - Molecular Target Synopsis

Protein


MFSD6, Major facilitator superfamily domain-containing protein 6
UniProt Q6ZSS7

Also Known as MFSD6_HUMAN, MFSD6, MMR2

May interact with HLA-B62.

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: MFSD6 is active in the following subcellular-locations: membrane.
GO terms: MFSD6 is active in the following subcellular-locations: integral component of membrane, membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project MFSD6 has gain in 2 cell-lines, loss in 1 cell-lines and no signal in 1002 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: MALME_3M, SR, CCRF_CEM

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: NCI-H345, SK-N-FI, DV-90

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: NHLF, HMEC, BJ

(see details)