Molecular Target Synopsis
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MAP3K15 (Q6ZN16) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 4BF2_A 82.87 0 STU
Protein kinase domain (99%) (view alignment) STK3 (Q13188) - 4LG4_A 35.16 1.0E-33 -
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 6E2M_B 82.19 0 KK7
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5V19_B 86.25 0 8V4
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4QMS_A 37.07 5.0E-33 1N1
Protein kinase domain (99%) (view alignment) STK26 (Q9P289) CAB39 (Q9Y376) 4FZD_B 35.8 8.0E-33 -
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 4BIC_A 82.87 0 IE4
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 6E2N_B 82.19 0 KK8
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5VIO_C 83.22 0 -
Protein kinase domain (99%) (view alignment) STK3 (Q13188) - 4LG4_C 35.16 1.0E-33 -
Protein kinase domain (99%) (view alignment) STK3 (Q13188) - 4LG4_F 35.16 1.0E-33 -
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 3A7F_A 37.07 4.0E-33 -
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) CAB39 (Q9Y376) 4O27_B 36.68 2.0E-32 ADP
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4QMM_A 37.07 5.0E-33 35R
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5VIL_C 83.22 0 9E1
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 2CLQ_B 83.22 0 STU
Protein kinase domain (99%) (view alignment) STK25 (O00506) CAB39 (Q9Y376) 4NZW_B 35.8 4.0E-32 J60
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4QMN_A 37.07 5.0E-33 DB8
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5UP3_B 86.25 0 8GS
Protein kinase domain (99%) (view alignment) STK3 (Q13188) SAV1 (Q9H4B6) 6AO5_A 35.8 4.0E-34 ANP
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4QMU_A 37.07 5.0E-33 SKE
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 3A7G_B 37.07 4.0E-33 -
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 4BID_A 82.87 0 IE8
Protein kinase domain (99%) (view alignment) PAK1 (Q13153) - 4ZJI_A 35.29 1.0E-34 4OQ
Protein kinase domain (99%) (view alignment) STK26 (Q9P289) - 3GGF_B 36.19 1.0E-33 GVD
Protein kinase domain (99%) (view alignment) STK3 (Q13188) - 5DH3_B 35.55 3.0E-34 5BS
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 6E2M_A 82.19 0 KK7
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4QO9_B 37.07 5.0E-33 627 PGE
Protein kinase domain (99%) (view alignment) STK3 (Q13188) RASSF5 (Q8WWW0) 4LGD_B 35.8 4.0E-34 ANP
Protein kinase domain (99%) (view alignment) STK3 (Q13188) - 4LG4_D 35.16 1.0E-33 -
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 3A7H_A 37.07 4.0E-33 ATP
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4QMV_A 37.07 5.0E-33 34W
Protein kinase domain (99%) (view alignment) STK3 (Q13188) RASSF5 (Q8WWW0) 4LGD_A 35.8 4.0E-34 ANP
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5V24_B 86.25 0 8V7
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 4BF2_B 82.87 0 STU
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 6E2O_A 82.19 0 S0L
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) CAB39L (Q9H9S4) 3ZHP_C 37.07 5.0E-33 -
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 3CKW_A 37.07 4.0E-33 -
Protein kinase domain (99%) (view alignment) STK3 (Q13188) RASSF5 (Q8WWW0) 4LGD_C 35.8 4.0E-34 ANP
Protein kinase domain (99%) (view alignment) STK26 (Q9P289) CAB39 (Q9Y376) 4FZA_B 35.8 8.0E-33 -
Protein kinase domain (99%) (view alignment) STK3 (Q13188) - 4LG4_E 35.16 1.0E-33 -
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) CAB39L (Q9H9S4) 3ZHP_D 37.07 5.0E-33 -
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5VIL_B 83.22 0 9E1
Protein kinase domain (99%) (view alignment) STK25 (O00506) - 2XIK_A 36.19 4.0E-33 J60
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 4BID_B 82.87 0 IE8
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4QMY_A 37.07 5.0E-33 STU
Protein kinase domain (99%) (view alignment) PAK1 (Q13153) - 4ZJI_D 35.29 1.0E-34 4OQ
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5VIL_A 83.22 0 9E1
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 3VW6_A 86.25 0 IM6
Domain of unknown function (DUF4071) (73%) (view alignment) MAP3K5 (Q99683) - 5ULM_A 60.41 0 -
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4QMZ_A 37.07 5.0E-33 B49
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5UP3_A 86.25 0 8GS
Protein kinase domain (99%) (view alignment) STK3 (Q13188) RASSF5 (Q8WWW0) 4LGD_D 35.8 4.0E-34 ANP
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4W8D_A 37.07 5.0E-33 3JA
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 2CLQ_A 83.22 0 STU
Protein kinase domain (99%) (view alignment) STK3 (Q13188) - 5DH3_A 35.55 3.0E-34 5BS
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 3CKX_A 37.07 4.0E-33 STU
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 3A7G_A 37.07 4.0E-33 -
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 3A7H_B 37.07 4.0E-33 ATP
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4QML_A 37.07 5.0E-33 ANP
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 4BHN_A 82.87 0 BH9
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 4BIB_B 82.87 0 IEO
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 4BIB_A 82.87 0 IEO
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4QMT_A 37.07 5.0E-33 H1N
Protein kinase domain (99%) (view alignment) STK26 (Q9P289) - 3GGF_A 36.19 1.0E-33 GVD
Protein kinase domain (99%) (view alignment) PAK1 (Q13153) - 4ZJJ_D 35.29 1.0E-34 4OR
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5VIO_D 83.22 0 9E4
Protein kinase domain (99%) (view alignment) STK26 (Q9P289) CAB39 (Q9Y376) 4FZF_B 35.8 8.0E-33 DKI
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4QMX_A 37.07 5.0E-33 H8H
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 6E2O_B 82.19 0 S0L
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4QMW_A 37.07 5.0E-33 KS1
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5UOR_A 86.25 0 8GV
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 4BIE_A 82.87 0 IE6
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5VIO_A 83.22 0 9E4
Protein kinase domain (99%) (view alignment) PAK1 (Q13153) - 4ZJJ_A 35.29 1.0E-34 4OR
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4U8Z_A 37.07 5.0E-33 3FE
Domain of unknown function (DUF4071) (73%) (view alignment) MAP3K5 (Q99683) - 5ULM_B 60.41 0 -
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 4BIE_B 82.87 0 IE6
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5UOR_B 86.25 0 8GV
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 6E2N_A 82.19 0 KK8
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4QMO_A 37.07 5.0E-33 34L
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5V19_A 86.25 0 8V4
Protein kinase domain (99%) (view alignment) STK4 (Q13043) - 3COM_B 36.58 5.0E-35 -
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4QO9_A 37.07 5.0E-33 627 PGE
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 3A7I_A 37.07 4.0E-33 ADE
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 4BIC_B 82.87 0 -
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 4BHN_B 82.87 0 BH9
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5UOX_B 86.25 0 8GY
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4QNA_A 37.07 5.0E-33 X11
Protein kinase domain (99%) (view alignment) PAK1 (Q13153) - 4ZJI_B 35.29 1.0E-34 4OQ
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 3VW6_B 86.25 0 IM6
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5VIO_B 83.22 0 9E4
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5UOX_A 86.25 0 8GY
Protein kinase domain (99%) (view alignment) STK4 (Q13043) - 3COM_A 36.58 5.0E-35 -
Protein kinase domain (99%) (view alignment) PAK1 (Q13153) - 4ZLO_A 35.29 8.0E-35 4PV
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5VIL_D 83.22 0 9E1
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4QMP_A 37.07 5.0E-33 DKI
Protein kinase domain (99%) (view alignment) PAK1 (Q13153) - 4ZJJ_B 35.29 1.0E-34 4OR
Protein kinase domain (99%) (view alignment) PAK1 (Q13153) - 4ZJJ_C 35.29 1.0E-34 4OR
Protein kinase domain (100%) (view alignment) MAP3K5 (Q99683) - 5V24_A 86.25 0 8V7
Protein kinase domain (99%) (view alignment) PAK1 (Q13153) - 4ZLO_B 35.29 8.0E-35 -
Protein kinase domain (99%) (view alignment) PAK1 (Q13153) - 4ZJI_C 35.29 1.0E-34 4OQ
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 3A7J_A 37.07 4.0E-33 ADP
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4W8E_A 37.07 4.0E-33 3JB
Protein kinase domain (99%) (view alignment) STK3 (Q13188) - 4LG4_B 35.16 1.0E-33 -
Protein kinase domain (99%) (view alignment) STK24 (Q9Y6E0) - 4QMQ_A 37.07 5.0E-33 34U