Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

SPNS3 (Q6ZMD2) - Overview - Molecular Target Synopsis

Protein


SPNS3, Protein spinster homolog 3
UniProt Q6ZMD2

Also Known as SPNS3_HUMAN, SPNS3

Sphingolipid transporter.

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: SPNS3 is active in the following subcellular-locations: membrane.
GO terms: SPNS3 is active in the following subcellular-locations: integral component of membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project SPNS3 has gain in 0 cell-lines, loss in 4 cell-lines and no signal in 1001 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: HL_60, SW_620, CCRF_CEM

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: OCI-AML2, SKM-1, ML-2

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: CD34-positive mobilized cell, SK-N-SH, NHLF

(see details)