Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

LMBR1L (Q6UX01) - Overview - Molecular Target Synopsis

Protein


LMBR1L, Protein LMBR1L
UniProt Q6UX01

Also Known as LMBRL_HUMAN, LMBR1L, KIAA1174, LIMR

Probable LCN1 receptor. May mediate LCN1 endocytosis.

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: LMBR1L is active in the following subcellular-locations: cell membrane.
GO terms: LMBR1L is active in the following subcellular-locations: integral component of plasma membrane, plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project LMBR1L has gain in 2 cell-lines, loss in 0 cell-lines and no signal in 1003 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: NCI-H187, SK-N-FI, MOLM-16

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, K562, HUVEC

(see details)