Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

LCN15 (Q6UWW0) - Overview - Molecular Target Synopsis

Protein


LCN15, Lipocalin-15
UniProt Q6UWW0

Also Known as LCN15_HUMAN, LCN15


2XST
CRYSTAL STRUCTURE OF THE HUMAN LIPOCALIN 15
RCSB/PDB
Inspect Structure
See all 3D Structures for LCN15

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
184ENSG00000177984ENST00000316144ENSP00000313833Q6UWW0-1

Sub-cellular localization


UniProt: LCN15 is active in the following subcellular-locations: secreted.
GO terms: LCN15 is active in the following subcellular-locations: extracellular region.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project LCN15 has gain in 2 cell-lines, loss in 1 cell-lines and no signal in 1002 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: HCC1534, VMRC-LCD, C3A

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)

3D Structures


For LCN15 there are:
1 structures (1 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis