Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

ARL9 (Q6T311) - Overview - Molecular Target Synopsis

Protein


ARL9, ADP-ribosylation factor-like protein 9
UniProt Q6T311

Also Known as ARL9_HUMAN, ARL9

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
187Q6T311-1
123ENSG00000196503ENST00000360096ENSP00000353210Q6T311-2

Gene Copy Number Variation


In COSMIC - Cell Lines Project ARL9 has gain in 2 cell-lines, loss in 5 cell-lines and no signal in 998 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: NCI_H522, RXF_393, HS578T

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: HCC1599, HCC1500, NCI-H1792

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, HSMM, NHLF

(see details)

3D Structures


At greater than 35% identity similarity to ARL9 there are:
71 structures (151 chains) solved
60 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


ARL9 has been screened with compounds ( bioactivities). (see details)