Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

RSBN1L (Q6PCB5) - Overview - Molecular Target Synopsis

Protein


RSBN1L, Round spermatid basic protein 1-like protein
UniProt Q6PCB5

Also Known as RSBNL_HUMAN, RSBN1L

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: RSBN1L is active in the following subcellular-locations: nucleus.
GO terms: RSBN1L is active in the following subcellular-locations: nucleus.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project RSBN1L has gain in 2 cell-lines, loss in 4 cell-lines and no signal in 999 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: K_562, HL_60, MCF7

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: OCI-M1, WSU-FSCCL, NCI-H1930

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, MCF-7, HSMM

(see details)

3D Structures


At greater than 35% identity similarity to RSBN1L there are:
1 structures (1 chains) solved
1 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis