Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

TATDN1 (Q6P1N9) - Overview - Molecular Target Synopsis

Protein


TATDN1, Putative deoxyribonuclease TATDN1
Enzyme Classification 3.1.21.-
UniProt Q6P1N9

Also Known as TATD1_HUMAN, TATDN1

Putative deoxyribonuclease.

2XIO
STRUCTURE OF PUTATIVE DEOXYRIBONUCLEASE TATDN1 ISOFORM A
RCSB/PDB
Inspect Structure
See all 3D Structures for TATDN1

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: TATDN1 is active in the following subcellular-locations: nucleus.
GO terms: TATDN1 is active in the following subcellular-locations: nucleoplasm.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project TATDN1 has gain in 39 cell-lines, loss in 0 cell-lines and no signal in 966 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: MCF7, HT29, OVCAR_8

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: MFM-223, HGC-27, KP4

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: MCF-7, NHLF, SK-N-SH

(see details)

3D Structures


For TATDN1 there are:
1 structures (1 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis