Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

MFSD5 (Q6N075) - Overview - Molecular Target Synopsis

Protein


MFSD5, Molybdate-anion transporter
UniProt Q6N075

Also Known as MFSD5_HUMAN, MFSD5

Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: MFSD5 is active in the following subcellular-locations: cell membrane.
GO terms: MFSD5 is active in the following subcellular-locations: integral component of membrane, membrane, plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project MFSD5 has gain in 1 cell-lines, loss in 1 cell-lines and no signal in 1003 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: T47D, ACHN, NCI_H226

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: SK23, T-47D, SNU-398

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: A549, NHLF, BJ

(see details)