Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

LMBRD2 (Q68DH5) - Overview - Molecular Target Synopsis

Protein


LMBRD2, LMBR1 domain-containing protein 2
UniProt Q68DH5

Also Known as LMBD2_HUMAN, LMBRD2

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
695ENSG00000164187ENST00000296603ENSP00000296603Q68DH5-1

Sub-cellular localization


UniProt: LMBRD2 is active in the following subcellular-locations: membrane.
GO terms: LMBRD2 is active in the following subcellular-locations: integral component of membrane, membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project LMBRD2 has gain in 39 cell-lines, loss in 0 cell-lines and no signal in 966 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: DU_145, HS578T, 786_0

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: NCI-H596, NCI-H209, HCC2302

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: K562, MCF-7, HSMM

(see details)