Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

Rgl2 (Q61193) - Overview - Molecular Target Synopsis

Protein


Rgl2, Ral guanine nucleotide dissociation stimulator-like 2
UniProt Q61193

Also Known as RGL2_MOUSE, Rgl2, Rab2l, Rlf

Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro. Interacts with SAMD9.

5CM8
STRUCTURAL BASIS FOR THE SELECTIVITY OF GUANINE NUCLEOTIDE EXCHANGE FACTORS FOR THE SMALL G-PROTEIN RAL
RCSB/PDB
Inspect Structure
See all 3D Structures for Rgl2

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
778Q61193-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project Rgl2 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For Rgl2 there are:
4 structures (6 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis