Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

copA (Q5ZWR1) - Overview - Molecular Target Synopsis

Protein


copA, Copper-exporting P-type ATPase
Enzyme Classification 7.2.2.8
UniProt Q5ZWR1

Also Known as COPA_LEGPH, copA

Couples the hydrolysis of ATP with the export of copper.

4BYG
ATPASE CRYSTAL STRUCTURE
RCSB/PDB
Inspect Structure
See all 3D Structures for copA

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform

Sub-cellular localization


UniProt: copA is active in the following subcellular-locations: cell inner membrane.
GO terms: copA is active in the following subcellular-locations: integral component of membrane, plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project copA has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For copA there are:
4 structures (7 chains) solved
2 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


copA has been screened with compounds ( bioactivities). (see details)