ABHD17B (Q5VST6) - Overview - Molecular Target Synopsis
ABHD17B, Alpha/beta hydrolase domain-containing protein 17B
Enzyme Classification 220.127.116.11
Also Known as AB17B_HUMAN, ABHD17B, C9orf77, FAM108B1
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins (PubMed:26701913). Has depalmitoylating activity towards DLG4/PSD95 (PubMed:26701913). Has depalmitoylating activity towards GAP43 (By similarity). Has depalmitoylating activity towards MAP6 (By similarity). Has depalmitoylating activity towards NRAS (PubMed:26701913).
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
UniProt: ABHD17B is active in the following subcellular-locations: cell junction, cell membrane, cell projection, dendritic spine, postsynaptic cell membrane, postsynaptic density, recycling endosome membrane, synapse.
GO terms: ABHD17B is active in the following subcellular-locations: anchored component of postsynaptic density membrane, anchored component of postsynaptic recycling endosome membrane, cell junction, dendritic spine, glutamatergic synapse, membrane, recycling endosome membrane.