Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

MFSD4B (Q5TF39) - Overview - Molecular Target Synopsis

Protein


MFSD4B, Sodium-dependent glucose transporter 1
UniProt Q5TF39

Also Known as MFS4B_HUMAN, MFSD4B, KIAA1919, NAGLT1

May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney.

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
518ENSG00000173214ENST00000368847ENSP00000357840Q5TF39-1

Sub-cellular localization


UniProt: MFSD4B is active in the following subcellular-locations: apical cell membrane.
GO terms: MFSD4B is active in the following subcellular-locations: apical plasma membrane, integral component of membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project MFSD4B has gain in 1 cell-lines, loss in 3 cell-lines and no signal in 1001 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are:

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are:

(see details)