Molecular Target Synopsis
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infC (Q5SKU2) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 02/07/2019)
Structural Druggability Help: Help

Chain-based assessment (last updated 02/07/2019)


Chains assessed9
Chains with at least one site assessed as druggable using the strict criteria0
Chains with at least one site assessed as druggable using the relaxed criteria3


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
5LMT_X Translation initiation factor IF-3 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.46 71.8 7.9 Yes No
2 empty 2.25 66 15.3 No No
3 empty 2.18 53 16.2 No No
4 empty 2.1 64.1 10 No No
5 empty 2.16 55.1 9.6 No No
6 empty 2.17 64.6 9.4 No No
7 empty 2.29 71.2 7.6 No No
8 empty 2.61 62.4 11.7 No No
9 empty 2.85 65.9 11.5 No No
10 empty 2.66 55.8 8 No No
5LMN_X Translation initiation factor IF-3 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.18 55.6 17.1 No No
2 empty 2.11 55 26.4 No No
3 empty 2.39 73.7 11.5 No No
4 empty 2.14 60 17.4 No No
5 empty 2.55 69 13.6 No No
6 empty 2.39 49.3 15.9 No No
7 empty 2.32 70.9 9.1 No No
8 empty 2.55 55.9 9.5 No No
9 empty 2.36 67.9 8.3 No No
10 empty 3.06 72.2 7.4 No No
5LMS_X Translation initiation factor IF-3 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.4 59 16.3 No No
2 empty 2.06 63.8 12.3 No No
3 empty 1.98 54.8 18.1 No No
4 empty 2.48 57 15.4 No No
5 empty 2.68 66 20.4 No No
6 empty 2.44 72 11.2 No No
7 empty 2.23 60.9 12.1 No No
8 empty 2.57 66.9 8.7 No No
9 empty 2.17 63.3 9.7 No No
10 empty 2.53 59 10.2 No No
5LMO_X Translation initiation factor IF-3 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.23 60.7 18.6 No No
2 empty 2.68 63.7 19.2 No No
3 empty 2.06 48.6 14.8 No No
4 empty 2.24 56.9 15.4 No No
5 empty 2.29 63 15.9 No No
6 empty 2.21 65.9 10.1 No No
7 empty 2.61 68.9 11.1 No No
8 empty 2.51 68.7 11 No No
9 empty 2.53 57.1 15.9 No No
10 empty 2.28 53.7 10 No No
5LMV_X Translation initiation factor IF-3 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.19 55.6 28.5 Yes No
2 empty 2.42 56.9 18.9 No No
3 empty 2.33 55.3 14.6 No No
4 empty 1.98 68.5 10 No No
5 empty 2.63 63.5 17.6 No No
6 empty 2.54 80.1 7.3 No No
7 empty 2.41 62.6 8.4 No No
8 empty 2.44 61.5 7.7 No No
9 empty 2.37 48.9 7.8 No No
10 empty 1.57 73.9 7.2 No No
5LMU_X Translation initiation factor IF-3 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.19 57.7 23.5 No No
2 empty 2.52 56.7 13.9 No No
3 empty 2.31 60.5 15.2 No No
4 empty 2.02 65.8 12.8 No No
5 empty 2.42 60.4 13.5 No No
6 empty 2.34 69 12.2 No No
7 empty 2.46 68.9 6.1 No No
8 empty 2.47 71.7 6.7 No No
9 empty 2.38 55.8 8.4 No No
10 empty 2.56 51.8 10.4 No No
5LMP_X Translation initiation factor IF-3 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.22 54.5 27.4 Yes No
2 empty 2.28 57.1 18.4 No No
3 empty 2.16 65.4 14.2 No No
4 empty 2.65 69.1 12.3 No No
5 empty 2.31 69.3 9.7 No No
6 empty 2.52 66.5 11.3 No No
7 empty 2.35 73.6 10.8 No No
8 empty 2.52 55.3 9.9 No No
9 empty 2.89 64.8 9.1 No No
10 empty 1.84 63.8 8.6 No No
5LMQ_X Translation initiation factor IF-3 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.1 60.8 22.8 No No
2 empty 2.41 62.4 15.7 No No
3 empty 2.47 60.6 20.1 No No
4 empty 2.18 68.7 12.8 No No
5 empty 2.51 73.1 9.2 No No
6 empty 2.02 49.8 10.7 No No
7 empty 2.17 60.3 15.4 No No
8 empty 2.47 60.6 12.5 No No
9 empty 2.45 60.9 14.4 No No
10 empty 2.7 66.5 7.2 No No
5LMR_X Translation initiation factor IF-3 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.09 54.6 23.4 No No
2 empty 2.75 64 19.1 No No
3 empty 2.5 59.1 23.5 No No
4 empty 2.48 58.4 18.2 No No
5 empty 2.42 75.2 8.7 No No
6 empty 2.63 72.8 11.2 No No
7 empty 1.85 66.4 10.1 No No
8 empty 2.87 62.2 11.6 No No
9 empty 2.13 63.7 12 No No
10 empty 2.46 56 10.1 No No
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score