rpoA (Q5SHR6) - Overview - Molecular Target Synopsis
rpoA, DNA-directed RNA polymerase subunit alpha
Enzyme Classification 22.214.171.124
Also Known as RPOA_THET8, rpoA
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
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