Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

rpsE (Q5SHQ5) - Overview - Molecular Target Synopsis

Protein


rpsE, 30S ribosomal protein S5
UniProt Q5SHQ5

Also Known as RS5_THET8, rpsE

With S4 and S12 plays an important role in translational accuracy., Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Binds mRNA in the 70S ribosome, positioning it for translation. Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.

6CAO
STRUCTURE OF THE RIBOSOMAL DECODING COMPLEX AT AMBIENT TEMPERATURE
RCSB/PDB
Inspect Structure
See all 3D Structures for rpsE

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
162Q5SHQ5-1, P27152-1, P62665-1

Sub-cellular localization


GO terms: rpsE is active in the following subcellular-locations: small ribosomal subunit.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project rpsE has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For rpsE there are:
120 structures (120 chains) solved
4 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis