Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

rpsS (Q5SHP2) - Overview - Molecular Target Synopsis

Protein


rpsS, 30S ribosomal protein S19
UniProt Q5SHP2

Also Known as RS19_THET8, rpsS

Located at the top of the head of the 30S subunit, extending towards the 50S subunit, which it may contact in the 70S complex. Contacts several RNA helices of the 16S rRNA. Part of the 30S ribosomal subunit. Forms a loose dimer with protein S13.

6MPF
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT COMPLEXED WITH A 2-THIOCYTIDINE (S2C32) AND INOSINE (I34) MODIFIED ANTICODON STEM LOOP (ASL) OF ESCHERICHIA COLI TRANSFER RNA ARGININE 1 (TRNAARG1) BOUND TO AN MRNA WITH AN CGC-CODON IN THE A-SITE AND PAROMOMYCIN
RCSB/PDB
Inspect Structure
See all 3D Structures for rpsS

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
93Q5SHP2-1, P62660-1, P80381-1

Sub-cellular localization


GO terms: rpsS is active in the following subcellular-locations: small ribosomal subunit.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project rpsS has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For rpsS there are:
125 structures (126 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis